Drug Information

Drug General Information
Drug ID
D0W7LK
Former ID
DNC002589
Drug Name
2-Propanol, Isopropanol
Drug Type
Small molecular drug
Indication Discovery agent Investigative [551393]
Structure
Download
2D MOL

3D MOL
Formula
C3H8O
Canonical SMILES
CC(C)O
InChI
1S/C3H8O/c1-3(2)4/h3-4H,1-2H3
InChIKey
KFZMGEQAYNKOFK-UHFFFAOYSA-N
PubChem Compound ID
3776
PubChem Substance ID
4963, 423976, 589444, 813293, 823371, 825349, 826612, 841342, 3135164, 5272310, 6436218, 7847205, 7888433, 7888444, 8006213, 8006303, 8006343, 8006719, 8007054, 8007624, 8007625, 8008177, 8008179, 8008181, 8008185, 8008188, 8008189, 8008222, 8008715, 8008832, 8009929, 8009948, 8010226, 8011055, 8011235, 8011519, 8011800, 8012365, 8013746, 8013748, 8013757, 8014331, 8014403, 8014510, 8014698, 8015403, 8015571, 8016872, 8018534, 8019056
Target and Pathway
Target(s) Nitric-oxide synthase, endothelial Target Info Inhibitor [551393]
Oxysterols receptor LXR-beta Target Info Inhibitor [551393]
Heme oxygenase Target Info Inhibitor [551393]
BioCyc Pathway Citrulline-nitric oxide cyclePWY-5874:Heme degradation
KEGG Pathway Arginine and proline metabolism
Metabolic pathways
Calcium signaling pathway
cGMP-PKG signaling pathway
HIF-1 signaling pathway
Sphingolipid signaling pathway
PI3K-Akt signaling pathway
VEGF signaling pathway
Platelet activation
Estrogen signaling pathway
Oxytocin signaling pathwayhsa00860:Porphyrin and chlorophyll metabolism
Mineral absorption
MicroRNAs in cancer
NetPath Pathway Wnt Signaling Pathway
PANTHER Pathway Angiogenesis
Endothelin signaling pathway
Interleukin signaling pathway
PI3 kinase pathway
VEGF signaling pathway
Pathway Interaction Database Plasma membrane estrogen receptor signaling
Validated transcriptional targets of AP1 family members Fra1 and Fra2
Angiopoietin receptor Tie2-mediated signaling
Thromboxane A2 receptor signaling
SHP2 signaling
VEGFR1 specific signals
Signaling events mediated by VEGFR1 and VEGFR2
PAR1-mediated thrombin signaling eventsrxr_vdr_pathway:RXR and RAR heterodimerization with other nuclear receptorfra_pathway:Validated transcriptional targets of AP1 family members Fra1 and Fra2
HIF-1-alpha transcription factor network
PathWhiz Pathway Porphyrin Metabolism
Reactome ROS production in response to bacteria
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
eNOS activation
Nitric oxide stimulates guanylate cyclase
VEGFR2 mediated vascular permeabilityR-HSA-383280:Nuclear Receptor transcription pathwayR-HSA-917937:Iron uptake and transport
WikiPathways ACE Inhibitor Pathway
EGF/EGFR Signaling Pathway
Myometrial Relaxation and Contraction Pathways
JAK/STAT
Corticotropin-releasing hormone
AGE/RAGE pathway
Endothelin Pathways
Leptin signaling pathway
Effects of Nitric Oxide
Metabolism of nitric oxide
AngiogenesisWP1982:SREBP signalling
Nuclear ReceptorsWP408:Oxidative Stress
Transcriptional activation by NRF2
NRF2 pathway
Nuclear Receptors Meta-Pathway
miR-targeted genes in squamous cell - TarBase
miR-targeted genes in muscle cell - TarBase
miR-targeted genes in lymphocytes - TarBase
miR-targeted genes in leukocytes - TarBase
miR-targeted genes in epithelium - TarBase
References
Ref 551393How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
Ref 551393How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.

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