Drug Information

Drug General Information
Drug ID
D0V8RY
Former ID
DIB009365
Drug Name
KR-30450
Synonyms
SKP-450; 1-[2(R)-(1,3-Dioxolan-2-yl)-2-methyl-6-nitro-2H-1-benzopyran-4-yl]pyrrolidin-2-one
Indication Hypertension [ICD9: 401; ICD10:I10-I16] Discontinued in Phase 1 [545884]
Structure
Download
2D MOL

3D MOL
CAS Number
CAS 146822-06-2
Target and Pathway
Target(s) Potassium channel Target Info Opener [531635], [534585]
References
Ref 545884Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800005207)
Ref 531635Therapeutic target database update 2012: a resource for facilitating target-oriented drug discovery. Nucleic Acids Res. 2012 Jan;40(Database issue):D1128-36.
Ref 534585Cardioprotective effects of KR-30450, a novel K+(ATP) opener, and its major metabolite KR-30818 on isolated rat hearts. Jpn J Pharmacol. 1998 Jan;76(1):65-73.

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