| Drug General Information |
| Drug ID |
D0V7HJ
|
| Former ID |
DNC006797
|
| Drug Name |
3-[2-(N,N,N-trimethylammonium)ethoxy]pyridine
|
| Drug Type |
Small molecular drug
|
| Indication |
Discovery agent
|
Investigative |
[1]
|
|---|
| Structure |
|
Download
2D MOL
3D MOL
|
| Formula |
C10H17N2O+
|
| Canonical SMILES |
C[N+](C)(C)CCOC1=CN=CC=C1
|
| InChI |
1S/C10H17N2O/c1-12(2,3)7-8-13-10-5-4-6-11-9-10/h4-6,9H,7-8H2,1-3H3/q+1
|
| InChIKey |
WBRKKKJHXQZXEM-UHFFFAOYSA-N
|
| PubChem Compound ID |
|
| Target and Pathway |
| Target(s) |
Neuronal acetylcholine receptor protein, beta-2 chain |
Target Info |
Inhibitor |
[1]
|
|---|
| Neuronal acetylcholine receptor protein, alpha-4 chain |
Target Info |
Inhibitor |
[1]
|
|
KEGG Pathway
|
Neuroactive ligand-receptor interaction
|
|
Cholinergic synapse
|
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Nicotine addictionhsa04080:Neuroactive ligand-receptor interaction
|
|
Nicotine addiction
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PANTHER Pathway
|
Nicotinic acetylcholine receptor signaling pathway
|
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Nicotine pharmacodynamics pathwayP00044:Nicotinic acetylcholine receptor signaling pathway
|
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Nicotine pharmacodynamics pathway
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Reactome
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Highly sodium permeable acetylcholine nicotinic receptors
|
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Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
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Highly calcium permeable nicotinic acetylcholine receptorsR-HSA-629587:Highly sodium permeable acetylcholine nicotinic receptors
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Highly calcium permeable nicotinic acetylcholine receptors
|
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WikiPathways
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SIDS Susceptibility Pathways
|
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Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
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Nicotine Activity on Dopaminergic NeuronsWP706:SIDS Susceptibility Pathways
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Nicotine Activity on Dopaminergic Neurons
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| References |
| REF 1 | Bioorg Med Chem Lett. 2006 Aug 15;16(16):4283-6. Epub 2006 Jun 9.Aryloxyethylamines: binding at alpha7 nicotinic acetylcholine receptors. |
|---|
