Drug Information
Drug General Information | |||||
---|---|---|---|---|---|
Drug ID |
D0T7US
|
||||
Former ID |
DAP000908
|
||||
Drug Name |
Eprosartan
|
||||
Synonyms |
SK&F 108566; SK-108566; SKF-108566; Teveten (TN); Eprosartan (USAN/INN); Eprosartan [USAN:BAN:INN]; SK&F-108566; (4-carboxybenzyl)imidazole-5-acrylic acid; (E)-2-Butyl-1-(p-carboxybenzyl)-alpha-2-thenylimidazole-5-acrylic acid; (E)-3-[2-n-butyl-1-{(4-carboxyphenyl)methyl}-1H-imidazol-5-yl]-2-(2-thienyl)methyl-2-propenoic acid; (E)-alpha{[2-butyl-1-[(4-carboxyphenyl)methyl]-1H-imidazole-5-yl]methylene}-2-thiopheneproprionic acid; 4-({2-butyl-5-[(1E)-2-carboxy-3-(2-thienyl)prop-1-en-1-yl]-1H-imidazol-1-yl}methyl)benzoic acid; 4-({2-butyl-5-[(1E)-2-carboxy-3-(thiophen-2-yl)prop-1-en-1-yl]-1H-imidazol-1-yl}methyl)benzoic acid; 4-[[2-butyl-5-[(E)-3-hydroxy-3-oxo-2-(thiophen-2-ylmethyl)prop-1-enyl]imidazol-1-yl]methyl]benzoic acid
|
||||
Drug Type |
Small molecular drug
|
||||
Therapeutic Class |
Antihypertensive Agents
|
||||
Company |
Abbott Laboratories
|
||||
Structure |
Download2D MOL |
||||
Formula |
C23H24N2O4S
|
||||
InChI |
InChI=1S/C23H24N2O4S/c1-2-3-6-21-24-14-19(12-18(23(28)29)13-20-5-4-11-30-20)25(21)15-16-7-9-17(10-8-16)22(26)27/h4-5,7-12,14H,2-3,6,13,15H2,1H3,(H,26,27)(H,28,29)/b18-12+
|
||||
InChIKey |
OROAFUQRIXKEMV-LDADJPATSA-N
|
||||
CAS Number |
CAS 133040-01-4
|
||||
PubChem Compound ID | |||||
PubChem Substance ID |
9670, 7979177, 8616481, 14929623, 17398013, 26757976, 39289969, 46506765, 48415948, 49658621, 49830795, 50064350, 50303490, 81092802, 85209073, 91612944, 92308966, 93166188, 103213560, 103924435, 113854438, 117814116, 121277912, 126682167, 127329712, 127329713, 127329714, 127329715, 127329716, 127329717, 127329718, 127329719, 127329720, 127329721, 127329722, 127329723, 131835100, 134223577, 134338185, 135026481, 135650236, 136367951, 137002491, 142300349, 144115951, 162161427, 163389404, 164814942, 175266444, 176484078
|
||||
ChEBI ID |
ChEBI:4814
|
||||
SuperDrug ATC ID |
C09CA02
|
||||
SuperDrug CAS ID |
cas=133040014
|
||||
Target and Pathway | |||||
Target(s) | Type-1 angiotensin II receptor | Target Info | Antagonist | [536887] | |
NetPath Pathway | TGF_beta_Receptor Signaling Pathway | ||||
Pathway Interaction Database | Arf6 trafficking events | ||||
Arf6 signaling events | |||||
Angiopoietin receptor Tie2-mediated signaling | |||||
PathWhiz Pathway | Angiotensin Metabolism | ||||
Muscle/Heart Contraction | |||||
References | |||||
Ref 536361 | Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77. Epub 2007 Feb 20. | ||||
Ref 541182 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 588). |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.