Drug General Information
Drug ID	D0SY6C
Former ID	DNC010805
Drug Name	7,4'-Dihydroxyflavone
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[530867]
Structure		Download 2D MOL 3D MOL
Formula	C15H10O4
Canonical SMILES	C1=CC(=CC=C1C2=CC(=O)C3=C(O2)C=C(C=C3)O)O
InChI	1S/C15H10O4/c16-10-3-1-9(2-4-10)14-8-13(18)12-6-5-11(17)7-15(12)19-14/h1-8,16-17H
InChIKey	LCAWNFIFMLXZPQ-UHFFFAOYSA-N
PubChem Compound ID	5282073
Target and Pathway
Target(s)	Cytochrome P450 19	Target Info	Inhibitor	[530867]
BioCyc Pathway	Superpathway of steroid hormone biosynthesis
	Estradiol biosynthesis II
	Estradiol biosynthesis I
KEGG Pathway	Steroid hormone biosynthesis
	Metabolic pathways
	Ovarian steroidogenesis
NetPath Pathway	FSH Signaling Pathway
PANTHER Pathway	Androgen/estrogene/progesterone biosynthesis
PathWhiz Pathway	Androgen and Estrogen Metabolism
Reactome	Endogenous sterols
WikiPathways	Metapathway biotransformation
	Tryptophan metabolism
	Oxidation by Cytochrome P450
	Ovarian Infertility Genes
	Metabolism of steroid hormones and vitamin D
	FSH signaling pathway
	Integrated Breast Cancer Pathway
	Phase 1 - Functionalization of compounds
References
Ref 530867	Bioorg Med Chem Lett. 2010 May 15;20(10):3050-64. Epub 2010 Apr 8.Pharmacophore modeling strategies for the development of novel nonsteroidal inhibitors of human aromatase (CYP19).
Ref 530867	Bioorg Med Chem Lett. 2010 May 15;20(10):3050-64. Epub 2010 Apr 8.Pharmacophore modeling strategies for the development of novel nonsteroidal inhibitors of human aromatase (CYP19).

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