Drug General Information
Drug ID	D0Q5BU
Former ID	DIB000926
Drug Name	MSH-1001
Synonyms	DNB-001; KR-31378; KR-31378); K+ channel activating compounds, Dongbu/KRICT
Indication	Ocular hypertension [ICD9: 365.04; ICD10:H40.0]		Phase 2	[548251]
Company	Danube Pharmaceuticals Inc; Korea Research Institute of Chemical Technology
Structure		Download 2D MOL 3D MOL
Canonical SMILES	[C@]1(Oc2c([C@H]([C@@H]1O)N/C(=N/C#N)/NCc1ccccc1)cc(N)c<br />c2)(C(OC)OC)C
CAS Number	CAS 335381-68-5
Target and Pathway
Target(s)	Potassium channel	Target Info	Opener	[530084]
References
Ref 548251	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800023795)
Ref 530084	KR-31378, a potassium-channel opener, induces the protection of retinal ganglion cells in rat retinal ischemic models. J Pharmacol Sci. 2009 Apr;109(4):511-7.

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