Drug Information
Drug General Information | |||||
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Drug ID |
D0P9RF
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Former ID |
DAP000371
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Drug Name |
Terazosin
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Synonyms |
Blavin; Flumarc; Fosfomic; Hytracin; Hytrin; Terazosabb; Terazosina; Terazosine; Terazosinum; Vasomet; Trazosin HCl; A 45975; Abbott 45975; A-45975; Hytrin (TN); Terazosabb (TN); Terazosin (INN); Terazosin [INN:BAN]; Terazosina [INN-Spanish]; Terazosine [INN-French]; Terazosinum [INN-Latin]; [4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl](tetrahydrofuran-2-yl)methanone; [4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl]-(oxolan-2-yl)methanone; 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-((tetrahydro-2-furanyl)carbonyl)piperazine; 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-(tetrahydro-2-furoyl)piperazine; 6,7-bis(methyloxy)-2-[4-(tetrahydrofuran-2-ylcarbonyl)piperazin-1-yl]quinazolin-4-amine; 6,7-dimethoxy-2-[4-(tetrahydrofuran-2-ylcarbonyl)piperazin-1-yl]quinazolin-4-amine
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Drug Type |
Small molecular drug
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Therapeutic Class |
Anticancer Agents
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Company |
Abbott Laboratories
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Structure |
Download2D MOL |
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Formula |
C19H25N5O4
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InChI |
InChI=1S/C19H25N5O4/c1-26-15-10-12-13(11-16(15)27-2)21-19(22-17(12)20)24-7-5-23(6-8-24)18(25)14-4-3-9-28-14/h10-11,14H,3-9H2,1-2H3,(H2,20,21,22)
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InChIKey |
VCKUSRYTPJJLNI-UHFFFAOYSA-N
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CAS Number |
CAS 63590-64-7
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PubChem Compound ID | |||||
PubChem Substance ID |
9337, 855611, 3206271, 5639778, 7980757, 8153320, 11466779, 11467899, 11486437, 14805011, 29224453, 46509129, 47285410, 47583257, 47953972, 48104698, 48328570, 48416598, 49698629, 50011223, 50085853, 50104877, 56464178, 57322756, 79795430, 85209414, 85788394, 90340975, 92309317, 92710520, 92729635, 93625098, 96025253, 103185057, 103941452, 104170187, 104309137, 117762845, 121362449, 124750263, 124800293, 124881671, 124881672, 125325415, 125355205, 126631797, 126685615, 129455086, 131549269, 134337681
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ChEBI ID |
ChEBI:9445
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SuperDrug ATC ID |
G04CA03
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SuperDrug CAS ID |
cas=063590647
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Target and Pathway | |||||
Target(s) | Alpha-1D adrenergic receptor | Target Info | Antagonist | [535079], [535647] | |
NetPath Pathway | IL2 Signaling Pathway | ||||
References | |||||
Ref 538289 | FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (ANDA) 074823. | ||||
Ref 542324 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7302). | ||||
Ref 535079 | Overexpression of the alpha1B-adrenergic receptor causes apoptotic neurodegeneration: multiple system atrophy. Nat Med. 2000 Dec;6(12):1388-94. | ||||
Ref 535647 | Induction of prostate apoptosis by alpha1-adrenoceptor antagonists: mechanistic significance of the quinazoline component. Prostate Cancer Prostatic Dis. 2002;5(2):88-95. |
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