| Drug General Information |
| Drug ID |
D0O3GO
|
| Former ID |
DNC003319
|
| Drug Name |
4-Androstenedione
|
| Drug Type |
Small molecular drug
|
| Indication |
Discovery agent
|
Investigative |
[1]
|
|---|
| Structure |
|
Download
2D MOL
3D MOL
|
| Formula |
C19H26O2
|
| Canonical SMILES |
CC12CCC(=O)C=C1CCC3C2CCC4(C3CCC4=O)C
|
| InChI |
1S/C19H26O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h11,14-16H,3-10H2,1-2H3/t14-,15-,16-,18-,19-/m0/s1
|
| InChIKey |
AEMFNILZOJDQLW-QAGGRKNESA-N
|
| CAS Number |
CAS 63-05-8
|
| PubChem Compound ID |
|
| PubChem Substance ID |
3575, 75016, 598429, 831360, 841441, 855972, 3162127, 7847119, 7885977, 8145630, 8153839, 14775551, 15962866, 17389251, 17389252, 17404677, 22400337, 24278247, 24702267, 24869681, 25621509, 26751578, 29215020, 29225131, 46508011, 47736685, 48035332, 48422859, 48424700, 48424701, 49856256, 50104208, 50362263, 53777220, 53790644, 56354941, 56354943, 56435876, 56436206, 56436633, 57323206, 57391483, 57650669, 71850513, 85148334, 85267761, 85279313, 92297726, 92303593, 92710448
|
| Target and Pathway |
| Target(s) |
Aldo-keto reductase family 1 member C3 |
Target Info |
Agonist |
[1]
|
|---|
| 3-beta-HSD |
Target Info |
Agonist |
[1]
|
| Estradiol 17 beta-dehydrogenase 1 |
Target Info |
Agonist |
[1]
|
|
BioCyc Pathway
|
Superpathway of steroid hormone biosynthesis
|
|
Allopregnanolone biosynthesis
|
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Androgen biosynthesisPWY-7305:Superpathway of steroid hormone biosynthesis
|
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Estradiol biosynthesis I
|
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KEGG Pathway
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Steroid hormone biosynthesis
|
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Arachidonic acid metabolism
|
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Metabolic pathways
|
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Ovarian steroidogenesishsa00140:Steroid hormone biosynthesis
|
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Ovarian steroidogenesis
|
|
NetPath Pathway
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TGF_beta_Receptor Signaling PathwayNetPath_25:FSH Signaling Pathway
|
|
PANTHER Pathway
|
Androgen/estrogene/progesterone biosynthesis
|
|
PathWhiz Pathway
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Arachidonic Acid MetabolismPW000045:Androgen and Estrogen Metabolism
|
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Reactome
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Retinoid metabolism and transportR-HSA-2453902:The canonical retinoid cycle in rods (twilight vision)
|
|
WikiPathways
|
Metapathway biotransformation
|
|
Benzo(a)pyrene metabolism
|
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Arachidonic acid metabolismWP496:Steroid Biosynthesis
|
|
Metabolism of steroid hormones and vitamin D
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|
Prostate Cancer
|
| References |
| REF 1 | How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. |
|---|
