Drug Information
Drug General Information | |||||
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Drug ID |
D0M7TO
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Former ID |
DAP001258
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Drug Name |
Tasosartan
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Synonyms |
Verdia; ANA-756; WAY-126756; Tasosartan (USAN/INN); WAY-ANA-756; 2,4-dimethyl-8-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]-5,6-dihydropyrido[2,3-d]pyrimidin-7-one; 2,4-dimethyl-8-{[2'-(2h-tetrazol-5-yl)biphenyl-4-yl]methyl}-5,8-dihydropyrido[2,3-d]pyrimidin-7(6h)-one
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Drug Type |
Small molecular drug
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Therapeutic Class |
Antihypertensive Agents
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Structure |
Download2D MOL |
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Formula |
C23H21N7O
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InChI |
InChI=1S/C23H21N7O/c1-14-18-11-12-21(31)30(23(18)25-15(2)24-14)13-16-7-9-17(10-8-16)19-5-3-4-6-20(19)22-26-28-29-27-22/h3-10H,11-13H2,1-2H3,(H,26,27,28,29)
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InChIKey |
ADXGNEYLLLSOAR-UHFFFAOYSA-N
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CAS Number |
CAS 145733-36-4
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PubChem Compound ID | |||||
PubChem Substance ID |
12014735, 14781918, 43118241, 46504809, 47207668, 50241161, 57314180, 85210063, 103271083, 103972483, 104253198, 104321954, 104826537, 117600003, 124757326, 125164130, 125823197, 126681832, 127392389, 134338495, 135016861, 137185590, 139561026, 140917228, 141045621, 143493280, 152233049, 152343908, 152344365, 160964640, 162011534, 163418539, 163849994, 164814968, 165238016, 172919626, 174527556, 178103480, 179149947, 179323284, 184545958, 198987382, 223659560, 224992574, 225380894, 226433336, 241036477, 242060035, 244153220, 249582367
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SuperDrug ATC ID |
C09CA05
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SuperDrug CAS ID |
cas=145733364
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Target and Pathway | |||||
Target(s) | Type-1 angiotensin II receptor | Target Info | Antagonist | [535061] | |
NetPath Pathway | TGF_beta_Receptor Signaling Pathway | ||||
Pathway Interaction Database | Arf6 trafficking events | ||||
Arf6 signaling events | |||||
Angiopoietin receptor Tie2-mediated signaling | |||||
PathWhiz Pathway | Angiotensin Metabolism | ||||
Muscle/Heart Contraction | |||||
References | |||||
Ref 536361 | Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77. Epub 2007 Feb 20. | ||||
Ref 541953 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6898). |
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