Drug Information

Drug General Information
Drug ID
D0M4ZK
Former ID
DNC007172
Drug Name
10-methoxy-ginkgolide C
Drug Type
Small molecular drug
Indication Discovery agent Investigative [528727]
Structure
Download
2D MOL

3D MOL
Formula
C21H26O11
Canonical SMILES
CC1C(=O)OC2C1(C34C5(C2O)C(C(C(C56C(C(=O)OC6O3)OC)C(C)(C<br />)C)O)C(=O)O4)O
InChI
1S/C21H26O11/c1-6-13(24)29-11-10(23)19-7-8(22)9(17(2,3)4)18(19)12(28-5)15(26)30-16(18)32-21(19,20(6,11)27)31-14(7)25/h6-12,16,22-23,27H,1-5H3/t6-,7+,8+,9+,10+,11+,12+,16+,18+,19+,20-,21+/m1/s1
InChIKey
RYOIKJMKJWXJLR-XWGAEZTCSA-N
PubChem Compound ID
44420890
PubChem Substance ID
103510677, 104085371, 134344377
Target and Pathway
Target(s) Glycine receptor Target Info Inhibitor [528727]
Glycine receptor alpha-1 chain Target Info Inhibitor [528727]
KEGG Pathway Neuroactive ligand-receptor interactionhsa04080:Neuroactive ligand-receptor interaction
Reactome Ligand-gated ion channel transportR-HSA-975298:Ligand-gated ion channel transport
WikiPathways Iron uptake and transport
References
Ref 528727J Med Chem. 2007 Apr 5;50(7):1610-7. Epub 2007 Mar 13.Probing the pharmacophore of ginkgolides as glycine receptor antagonists.
Ref 528727J Med Chem. 2007 Apr 5;50(7):1610-7. Epub 2007 Mar 13.Probing the pharmacophore of ginkgolides as glycine receptor antagonists.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.