| Drug General Information |
| Drug ID |
D0L7FS
|
| Former ID |
DNC004871
|
| Drug Name |
N-hydroxycarbamate derivative
|
| Indication |
Discovery agent
|
Investigative |
[1]
|
|---|
| Structure |
|
Download
2D MOL
3D MOL
|
| Target and Pathway |
| Target(s) |
Histamine H1 receptor |
Target Info |
Inhibitor |
[1]
|
|---|
| mRNA of human 5-lipoxygenase |
Target Info |
Inhibitor |
[1]
|
|
BioCyc Pathway
|
Aspirin-triggered lipoxin biosynthesis
|
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Resolvin D biosynthesis
|
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Leukotriene biosynthesis
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Lipoxin biosynthesis
|
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Aspirin triggered resolvin D biosynthesis
|
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Aspirin triggered resolvin E biosynthesis
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KEGG Pathway
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Calcium signaling pathway
|
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Neuroactive ligand-receptor interaction
|
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Inflammatory mediator regulation of TRP channelshsa00590:Arachidonic acid metabolism
|
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Metabolic pathways
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Serotonergic synapse
|
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Ovarian steroidogenesis
|
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Toxoplasmosis
|
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NetPath Pathway
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IL4 Signaling Pathway
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PANTHER Pathway
|
Histamine H1 receptor mediated signaling pathway
|
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PathWhiz Pathway
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Arachidonic Acid Metabolism
|
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Reactome
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Histamine receptors
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G alpha (q) signalling events
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WikiPathways
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Monoamine GPCRs
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GPCRs, Class A Rhodopsin-like
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IL-4 Signaling Pathway
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Gastrin-CREB signalling pathway via PKC and MAPK
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GPCR ligand binding
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GPCR downstream signalingWP2650:Arachidonic acid metabolism
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Eicosanoid Synthesis
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Selenium Micronutrient Network
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| References |
| REF 1 | Bioorg Med Chem Lett. 2005 Feb 15;15(4):1083-5.5-Lipoxygenase inhibition by N-hydroxycarbamates in dual-function compounds. |
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