Drug Information
Drug General Information | |||||
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Drug ID |
D0J2NB
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Former ID |
DIB008260
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Drug Name |
KRH-594
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Synonyms |
KRG-594; WK-1492; WK-1492-2K
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Drug Type |
Small molecular drug
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Indication | Hypertension [ICD9: 401; ICD10:I10-I16] | Discontinued in Phase 2 | [546398] | ||
Company |
Wakunaga Pharmaceutical Co Ltd
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Structure |
Download2D MOL |
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Formula |
C25H22KN7O3S
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Canonical SMILES |
c1(c(c2[n-]nnn2)cccc1)c1ccc(cc1)Cn1/c(=N/C(=O)C2=C(CCC2<br />)C(=O)[O-])/sc(n1)CC.[K+].[K+]
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CAS Number |
CAS 169328-25-0
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PubChem Compound ID | |||||
Target and Pathway | |||||
Target(s) | Type-1 angiotensin II receptor | Target Info | Antagonist | [526535] | |
NetPath Pathway | TGF_beta_Receptor Signaling Pathway | ||||
Pathway Interaction Database | Arf6 trafficking events | ||||
Arf6 signaling events | |||||
Angiopoietin receptor Tie2-mediated signaling | |||||
PathWhiz Pathway | Angiotensin Metabolism | ||||
Muscle/Heart Contraction | |||||
References |
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