| Drug General Information |
| Drug ID |
D0HQ4M
|
| Former ID |
DNC014024
|
| Drug Name |
Isopropyl dodecylfluorophosphonate
|
| Drug Type |
Small molecular drug
|
| Indication |
Discovery agent
|
Investigative |
[1]
|
|---|
| Structure |
|
Download
2D MOL
3D MOL
|
| Formula |
C15H32FO2P
|
| Canonical SMILES |
CCCCCCCCCCCCP(=O)(OC(C)C)F
|
| InChI |
1S/C15H32FO2P/c1-4-5-6-7-8-9-10-11-12-13-14-19(16,17)18-15(2)3/h15H,4-14H2,1-3H3
|
| InChIKey |
SFRALHFBKRAJPW-UHFFFAOYSA-N
|
| PubChem Compound ID |
|
| Target and Pathway |
| Target(s) |
Fatty-acid amide hydrolase |
Target Info |
Inhibitor |
[1]
|
|---|
| Cannabinoid receptor 1 |
Target Info |
Inhibitor |
[1]
|
| Acetylcholinesterase |
Target Info |
Inhibitor |
[1]
|
|
BioCyc Pathway
|
Anandamide degradation
|
|
KEGG Pathway
|
Retrograde endocannabinoid signalinghsa04015:Rap1 signaling pathway
|
|
Neuroactive ligand-receptor interaction
|
|
Retrograde endocannabinoid signalinghsa00564:Glycerophospholipid metabolism
|
|
Cholinergic synapse
|
|
PANTHER Pathway
|
Anandamide degradationP05730:Endogenous cannabinoid signalingP00042:Muscarinic acetylcholine receptor 1 and 3 signaling pathway
|
|
Muscarinic acetylcholine receptor 2 and 4 signaling pathway
|
|
Nicotinic acetylcholine receptor signaling pathway
|
|
Pathway Interaction Database
|
N-cadherin signaling eventsatf2_pathway:ATF-2 transcription factor network
|
|
PathWhiz Pathway
|
Phospholipid Biosynthesis
|
|
Reactome
|
Class A/1 (Rhodopsin-like receptors)
|
|
G alpha (i) signalling events
|
|
WikiPathways
|
GPCRs, Class A Rhodopsin-like
|
|
Small Ligand GPCRs
|
|
BDNF signaling pathway
|
|
GPCR ligand binding
|
|
GPCR downstream signaling
|
|
GPCRs, OtherWP727:Monoamine Transport
|
|
Biogenic Amine Synthesis
|
|
Acetylcholine Synthesis
|
|
Integrated Pancreatic Cancer Pathway
|
| References |
| REF 1 | Nat Chem Biol. 2008 Jun;4(6):373-8. Epub 2008 Apr 27.Activation of the endocannabinoid system by organophosphorus nerve agents. |
|---|
