Drug General Information
Drug ID
D0H4GB
Former ID
DPR000027
Drug Name
CB1 antagonist, Bayer
Drug Type
Small molecular drug
Indication Obesity [ICD9: 278; ICD10:E66] Preclinical [536122]
Company
Bayer
Structure
Download
2D MOL

3D MOL

Formula
C14H10Cl2NO2-
Canonical SMILES
CC1=C(C(=C(C=C1)Cl)NC2=CC=CC=C2C(=O)[O-])Cl
InChI
1S/C14H11Cl2NO2/c1-8-6-7-10(15)13(12(8)16)17-11-5-3-2-4-9(11)14(18)19/h2-7,17H,1H3,(H,18,19)/p-1
InChIKey
SBDNJUWAMKYJOX-UHFFFAOYSA-M
CAS Number
CAS 168273-06-1
PubChem Compound ID
PubChem Substance ID
SuperDrug ATC ID
M01AG04
SuperDrug CAS ID
cas=000644622
Target and Pathway
Target(s) Cannabinoid receptor 1 Target Info Antagonist [536122]
KEGG Pathway Rap1 signaling pathway
Neuroactive ligand-receptor interaction
Retrograde endocannabinoid signaling
PANTHER Pathway Endogenous cannabinoid signaling
Pathway Interaction Database N-cadherin signaling events
Reactome Class A/1 (Rhodopsin-like receptors)
G alpha (i) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Small Ligand GPCRs
BDNF signaling pathway
GPCR ligand binding
GPCR downstream signaling
GPCRs, Other
References
Ref 536122Emerging drugs for obesity: linking novel biological mechanisms to pharmaceutical pipelines. Expert Opin Emerg Drugs. 2005 Aug;10(3):643-60.
Ref 536122Emerging drugs for obesity: linking novel biological mechanisms to pharmaceutical pipelines. Expert Opin Emerg Drugs. 2005 Aug;10(3):643-60.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.