Drug General Information
Drug ID	D0H4BJ
Former ID	DNC000970
Drug Name	Muscarine
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[540612]
Structure		Download 2D MOL 3D MOL
Formula	C9H20NO2+
InChI	InChI=1S/C9H20NO2/c1-7-9(11)5-8(12-7)6-10(2,3)4/h7-9,11H,5-6H2,1-4H3/q+1/t7-,8-,9+/m0/s1
InChIKey	UQOFGTXDASPNLL-XHNCKOQMSA-N
PubChem Compound ID	9308
PubChem Substance ID	9676, 7980043, 8156660, 11111401, 16472328, 29227917, 47349362, 49994743, 50111175, 57325573, 78373694, 90341763, 103173882, 103919666, 103921290, 104320164, 121368218, 124750050, 125086646, 129406434, 134222100, 134975443, 137101313, 152105966, 162222781, 178100822, 198939053, 223440417, 226458662
Target and Pathway
Target(s)	Muscarinic acetylcholine receptor M5	Target Info	Agonist	[535437]
KEGG Pathway	Calcium signaling pathway
	Neuroactive ligand-receptor interaction
	Cholinergic synapse
	Regulation of actin cytoskeleton
PANTHER Pathway	Alzheimer disease-amyloid secretase pathway
	Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
Reactome	Muscarinic acetylcholine receptors
	G alpha (q) signalling events
WikiPathways	Monoamine GPCRs
	Calcium Regulation in the Cardiac Cell
	Regulation of Actin Cytoskeleton
	GPCRs, Class A Rhodopsin-like
	Gastrin-CREB signalling pathway via PKC and MAPK
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 540612	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 3996).
Ref 535437	The effects of the antagonists of muscarinic acetylcholine receptor subtypes in rat brain on urinary bladder contraction. Nippon Hinyokika Gakkai Zasshi. 2002 Mar;93(3):427-34.

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