| Drug General Information |
| Drug ID |
D0H1GU
|
| Former ID |
DNC002683
|
| Drug Name |
Double Oxidized Cysteine
|
| Drug Type |
Small molecular drug
|
| Indication |
Discovery agent
|
Investigative |
[1]
|
|---|
| Structure |
|
Download
2D MOL
3D MOL
|
| Formula |
C3H6NO4S
|
| PubChem Compound ID |
|
| Target and Pathway |
| Target(s) |
Alpha-glucosidase |
Target Info |
Inhibitor |
[1]
|
|---|
| mRNA of Protein tyrosine phosphatase-1B |
Target Info |
Inhibitor |
[1]
|
| Maltase-glucoamylase, intestinal |
Target Info |
Inhibitor |
[1]
|
| M-phase inducer phosphatase 2 |
Target Info |
Inhibitor |
[1]
|
| Cell division protein kinase 2 |
Target Info |
Inhibitor |
[1]
|
| Beta crystallin B1 |
Target Info |
Inhibitor |
[1]
|
| Prolyl endopeptidase |
Target Info |
Inhibitor |
[1]
|
| Peptide deformylase |
Target Info |
Inhibitor |
[1]
|
|
KEGG Pathway
|
Adherens junction
|
|
Insulin signaling pathwayhsa00052:Galactose metabolism
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Starch and sucrose metabolism
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Metabolic pathways
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Carbohydrate digestion and absorptionhsa04010:MAPK signaling pathway
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Cell cycle
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Progesterone-mediated oocyte maturation
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MicroRNAs in cancerhsa04068:FoxO signaling pathway
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Oocyte meiosis
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p53 signaling pathway
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PI3K-Akt signaling pathway
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Hepatitis B
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Measles
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Herpes simplex infection
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Epstein-Barr virus infection
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Pathways in cancer
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Viral carcinogenesis
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Prostate cancer
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Small cell lung cancerhsa04614:Renin-angiotensin system
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NetPath Pathway
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FSH Signaling PathwayNetPath_14:IL2 Signaling Pathway
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TGF_beta_Receptor Signaling Pathway
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Wnt Signaling PathwayNetPath_11:TCR Signaling Pathway
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PANTHER Pathway
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Cadherin signaling pathwayP00059:p53 pathway
|
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p53 pathway feedback loops 2P04395:Vasopressin synthesis
|
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Pathway Interaction Database
|
Insulin Pathway
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Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
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Signaling events mediated by PTP1B
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Calcineurin-regulated NFAT-dependent transcription in lymphocytes
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Signaling events mediated by TCPTP
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IGF1 pathway
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EGF receptor (ErbB1) signaling pathway
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Posttranslational regulation of adherens junction stability and dissassembly
|
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PDGFR-beta signaling pathway
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N-cadherin signaling eventsplk1_pathway:PLK1 signaling events
|
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FOXM1 transcription factor network
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p38 signaling mediated by MAPKAP kinases
|
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Aurora A signalingsmad2_3nuclearpathway:Regulation of nuclear SMAD2/3 signaling
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Signaling events mediated by PRL
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p73 transcription factor network
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E2F transcription factor network
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ATR signaling pathway
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mTOR signaling pathway
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IL2-mediated signaling events
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FoxO family signaling
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BARD1 signaling events
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p53 pathway
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Regulation of retinoblastoma protein
|
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PathWhiz Pathway
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Starch and Sucrose Metabolism
|
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Reactome
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Integrin alphaIIb beta3 signaling
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Regulation of IFNG signaling
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Regulation of IFNA signaling
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Growth hormone receptor signalingR-HSA-157881:Cyclin B2 mediated events
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Cyclin A/B1 associated events during G2/M transition
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Cyclin A:Cdk2-associated events at S phase entryR-HSA-1538133:G0 and Early G1
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Activation of ATR in response to replication stress
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Regulation of APC/C activators between G1/S and early anaphase
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SCF(Skp2)-mediated degradation of p27/p21
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Senescence-Associated Secretory Phenotype (SASP)
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DNA Damage/Telomere Stress Induced Senescence
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Processing of DNA double-strand break ends
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G2 Phase
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Orc1 removal from chromatin
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Cyclin E associated events during G1/S transition
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p53-Dependent G1 DNA Damage Response
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Cyclin A:Cdk2-associated events at S phase entry
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Meiotic recombination
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Factors involved in megakaryocyte development and platelet production
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WikiPathways
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Insulin Signaling
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Growth hormone receptor signaling
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Leptin signaling pathway
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Interferon gamma signaling
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Interferon alpha/beta signaling
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Integrin alphaIIb beta3 signalingWP1848:Metabolism of carbohydratesWP615:Senescence and Autophagy in Cancer
|
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MAPK Signaling Pathway
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Retinoblastoma (RB) in Cancer
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Prostate Cancer
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Integrated Breast Cancer Pathway
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Integrated Cancer pathway
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Mitotic G2-G2/M phases
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Cell CycleWP707:DNA Damage Response
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ID signaling pathway
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DNA Replication
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G1 to S cell cycle control
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M/G1 Transition
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S Phase
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Meiotic Recombination
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Aryl Hydrocarbon Receptor
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ATM Signaling Pathway
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Spinal Cord Injury
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Integrated Pancreatic Cancer Pathway
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Oncostatin M Signaling Pathway
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Signaling Pathways in Glioblastoma
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TSH signaling pathway
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Synthesis of DNA
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Regulation of DNA replication
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Mitotic G1-G1/S phases
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Factors involved in megakaryocyte development and platelet production
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Cell Cycle
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APC/C-mediated degradation of cell cycle proteins
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Cell Cycle Checkpoints
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miRNA Regulation of DNA Damage Response
|
| References |
| REF 1 | How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. |
|---|
