Drug General Information
Drug ID	D0GT4N
Former ID	DIB012575
Drug Name	BRL-55834
Drug Type	Small molecular drug
Indication	Chronic obstructive pulmonary disease [ICD9: 490-492, 494-496; ICD10:J40-J44, J47]		Discontinued in Phase 2	[544932]
Company	SmithKline Beecham plc
Structure		Download 2D MOL 3D MOL
Formula	C18H20F5NO3
Canonical SMILES	c12[C@@H](N3C(=O)CCCC3)[C@@H](C(Oc1ccc(C(C(F)(F)F)(F)F)<br />c2)(C)C)O
CAS Number	CAS 131899-25-7
PubChem Compound ID	131442
Target and Pathway
Target(s)	Potassium channel	Target Info	Opener	[534028]
References
Ref 544932	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800001581)
Ref 534028	Comparison of the airways relaxant and hypotensive potencies of the potassium channel activators BRL 55834 and levcromakalim (BRL 38227) in vivo in guinea-pigs and rats. Br J Pharmacol. 1993 Aug;109(4):1133-9.

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