| Drug General Information |
| Drug ID |
D0G6RT
|
| Former ID |
DNC002628
|
| Drug Name |
(R)-4-Amino-Isoxazolidin-3-One
|
| Drug Type |
Small molecular drug
|
| Indication |
Discovery agent
|
Investigative |
[1]
|
|---|
| Structure |
|
Download
2D MOL
3D MOL
|
| Formula |
C3H6N2O2
|
| Canonical SMILES |
C1C(C(=O)NO1)N
|
| InChI |
1S/C3H6N2O2/c4-2-1-7-5-3(2)6/h2H,1,4H2,(H,5,6)/t2-/m1/s1
|
| InChIKey |
DYDCUQKUCUHJBH-UWTATZPHSA-N
|
| PubChem Compound ID |
|
| PubChem Substance ID |
10257, 602895, 829389, 841629, 3139717, 7847941, 7885338, 7979010, 8149277, 8153915, 11110913, 11110914, 11110915, 11112194, 11112195, 11335273, 11360512, 11363754, 11366316, 11368878, 11371441, 11374029, 11377040, 11461484, 11467117, 11468237, 11483744, 11486765, 11487900, 11490187, 11492120, 11494674, 12014545, 15170469, 17404815, 24277962, 24858076, 24892907, 24892979, 25622405, 26611680, 26679210, 26719637, 29214856, 29225230, 46386864, 46392863, 46506865, 46507135, 47216632
|
| Target and Pathway |
| Target(s) |
Alanine racemase,biosynthetic |
Target Info |
Inhibitor |
[1]
|
|---|
| NMDA receptor subunit NR1 |
Target Info |
Inhibitor |
[1]
|
|
KEGG Pathway
|
Ras signaling pathway
|
|
Rap1 signaling pathway
|
|
Calcium signaling pathway
|
|
cAMP signaling pathway
|
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Neuroactive ligand-receptor interaction
|
|
Circadian entrainment
|
|
Long-term potentiation
|
|
Glutamatergic synapse
|
|
Alzheimer's disease
|
|
Amyotrophic lateral sclerosis (ALS)
|
|
Huntington's disease
|
|
Cocaine addiction
|
|
Amphetamine addiction
|
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Nicotine addiction
|
|
Alcoholism
|
|
PANTHER Pathway
|
Huntington disease
|
|
Ionotropic glutamate receptor pathway
|
|
Metabotropic glutamate receptor group III pathway
|
|
Metabotropic glutamate receptor group I pathway
|
|
Muscarinic acetylcholine receptor 1 and 3 signaling pathway
|
|
Reactome
|
EPHB-mediated forward signaling
|
|
Unblocking of NMDA receptor, glutamate binding and activation
|
|
CREB phosphorylation through the activation of CaMKII
|
|
Ras activation uopn Ca2+ infux through NMDA receptor
|
|
RAF/MAP kinase cascade
|
|
WikiPathways
|
SIDS Susceptibility Pathways
|
|
Hypothetical Network for Drug Addiction
|
|
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
|
|
Spinal Cord Injury
|
|
BDNF signaling pathway
|
|
Alzheimers Disease
|
| References |
| REF 1 | How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. |
|---|
