Drug General Information
Drug ID	D0G5CP
Former ID	DNC010811
Drug Name	4'-(6-Methoxypyridin-3-yl)biphenyl-3-ol
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[530868]
Structure		Download 2D MOL 3D MOL
Formula	C18H15NO2
Canonical SMILES	COC1=NC=C(C=C1)C2=CC=C(C=C2)C3=CC(=CC=C3)O
InChI	1S/C18H15NO2/c1-21-18-10-9-16(12-19-18)14-7-5-13(6-8-14)15-3-2-4-17(20)11-15/h2-12,20H,1H3
InChIKey	JEDOKEGGMJNKGY-UHFFFAOYSA-N
PubChem Compound ID	46887511
Target and Pathway
Target(s)	Estradiol 17 beta-dehydrogenase 1	Target Info	Inhibitor	[530868]
BioCyc Pathway	Superpathway of steroid hormone biosynthesis
	Estradiol biosynthesis I
KEGG Pathway	Steroid hormone biosynthesis
	Metabolic pathways
	Ovarian steroidogenesis
NetPath Pathway	FSH Signaling Pathway
PANTHER Pathway	Androgen/estrogene/progesterone biosynthesis
PathWhiz Pathway	Androgen and Estrogen Metabolism
Reactome	The canonical retinoid cycle in rods (twilight vision)
WikiPathways	Steroid Biosynthesis
	Metabolism of steroid hormones and vitamin D
	Prostate Cancer
References
Ref 530868	Bioorg Med Chem. 2010 May 15;18(10):3494-505. Epub 2010 Mar 29.Novel estrone mimetics with high 17beta-HSD1 inhibitory activity.
Ref 530868	Bioorg Med Chem. 2010 May 15;18(10):3494-505. Epub 2010 Mar 29.Novel estrone mimetics with high 17beta-HSD1 inhibitory activity.

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