Drug Information
Drug General Information | |||||
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Drug ID |
D0F3FC
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Former ID |
DIB007845
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Drug Name |
GSK-650394
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Synonyms |
SGK-1 inhibitor (prostate cancer), GlaxoSmithKline
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Drug Type |
Small molecular drug
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Indication | Prostate cancer [ICD9: 185; ICD10:C61] | Investigative | [542939] | ||
Company |
GlaxoSmithKline plc
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Structure |
Download2D MOL |
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Formula |
C25H22N2O2
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InChI |
InChI=1S/C25H22N2O2/c28-25(29)20-11-10-18(12-21(20)17-8-4-5-9-17)23-15-27-24-22(23)13-19(14-26-24)16-6-2-1-3-7-16/h1-3,6-7,10-15,17H,4-5,8-9H2,(H,26,27)(H,28,29)
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InChIKey |
WVSBGSNVCDAMCF-UHFFFAOYSA-N
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PubChem Compound ID | |||||
PubChem Substance ID |
56372317, 57539305, 103691849, 104137542, 135684976, 135698891, 161004290, 163125605, 172096672, 172650544, 174006394, 177749675, 180371701, 198978264, 203081890, 204371603, 208265528, 210275191, 210280830, 223427127, 223704823, 229755473, 241376526, 242078818, 247483342, 249565720, 249617914, 251963080, 252151146, 252157366, 252160262, 252450683, 252471858, 252543666
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Target and Pathway | |||||
Target(s) | Serine/threonine-protein kinase Sgk1 | Target Info | Inhibitor | [542938] | |
Pathway Interaction Database | Insulin Pathway | ||||
Glucocorticoid receptor regulatory network | |||||
mTOR signaling pathway | |||||
FoxO family signaling | |||||
Class I PI3K signaling events | |||||
Reactome | Stimuli-sensing channels | ||||
References |
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