Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0E2BB
|
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| Former ID |
DNC008751
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| Drug Name |
Naltrexone-6-beta-ol
|
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| Drug Type |
Small molecular drug
|
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| Indication | Discovery agent | Investigative | [529816] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C20H25NO4
|
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| Canonical SMILES |
C1CC1CN2CCC34C5C(CCC3(C2CC6=C4C(=C(C=C6)O)O5)O)O
|
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| InChI |
1S/C20H25NO4/c22-13-4-3-12-9-15-20(24)6-5-14(23)18-19(20,16(12)17(13)25-18)7-8-21(15)10-11-1-2-11/h3-4,11,14-15,18,22-24H,1-2,5-10H2/t14-,15-,18+,19+,20-/m1/s1
|
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| InChIKey |
JLVNEHKORQFVQJ-PYIJOLGTSA-N
|
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Delta-type opioid receptor | Target Info | Inhibitor | [529816] | |
| Kappa-type opioid receptor | Target Info | Inhibitor | [529816] | ||
| Mu-type opioid receptor | Target Info | Inhibitor | [529816] | ||
| NetPath Pathway | TCR Signaling Pathway | ||||
| PANTHER Pathway | Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | ||||
| Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway | |||||
| Enkephalin release | |||||
| Opioid proenkephalin pathway | |||||
| Opioid proopiomelanocortin pathwayP00026:Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | |||||
| Opioid prodynorphin pathwayP00026:Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | |||||
| Pathway Interaction Database | IL4-mediated signaling events | ||||
| References | |||||
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