Drug Information

Drug General Information
Drug ID
D0B8AN
Former ID
DNC006975
Drug Name
JWH-347
Drug Type
Small molecular drug
Indication Discovery agent Investigative [528355]
Structure
Download
2D MOL

3D MOL
Formula
C30H27NO
Canonical SMILES
CCCCCN1C=C(C=C1C2=CC3=CC=CC=C3C=C2)C(=O)C4=CC=CC5=CC=CC<br />=C54
InChI
1S/C30H27NO/c1-2-3-8-18-31-21-26(30(32)28-15-9-13-23-11-6-7-14-27(23)28)20-29(31)25-17-16-22-10-4-5-12-24(22)19-25/h4-7,9-17,19-21H,2-3,8,18H2,1H3
InChIKey
WYOWIOBJNTYRNN-UHFFFAOYSA-N
PubChem Compound ID
44418372
Target and Pathway
Target(s) Cannabinoid receptor 1 Target Info Inhibitor [528355]
Cannabinoid receptor 2 Target Info Inhibitor [528355]
KEGG Pathway Rap1 signaling pathway
Neuroactive ligand-receptor interaction
Retrograde endocannabinoid signalinghsa04080:Neuroactive ligand-receptor interaction
PANTHER Pathway Endogenous cannabinoid signaling
Pathway Interaction Database N-cadherin signaling events
Reactome Class A/1 (Rhodopsin-like receptors)
G alpha (i) signalling eventsR-HSA-373076:Class A/1 (Rhodopsin-like receptors)
G alpha (i) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Small Ligand GPCRs
BDNF signaling pathway
GPCR ligand binding
GPCR downstream signaling
GPCRs, OtherWP455:GPCRs, Class A Rhodopsin-like
References
Ref 528355Bioorg Med Chem Lett. 2006 Oct 15;16(20):5432-5. Epub 2006 Aug 4.1-Alkyl-2-aryl-4-(1-naphthoyl)pyrroles: new high affinity ligands for the cannabinoid CB1 and CB2 receptors.
Ref 528355Bioorg Med Chem Lett. 2006 Oct 15;16(20):5432-5. Epub 2006 Aug 4.1-Alkyl-2-aryl-4-(1-naphthoyl)pyrroles: new high affinity ligands for the cannabinoid CB1 and CB2 receptors.

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