Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0B0PW
|
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| Former ID |
DNC001176
|
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| Drug Name |
Pyrimidinyl acylthiourea
|
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| Indication | Discovery agent | Investigative | [1], [2], [3] | ||
| Formula |
C10H14N4O2S
|
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| Target and Pathway | |||||
| Target(s) | RNA-dependentRNA polymerase | Target Info | Inhibitor | [1], [2], [3] | |
| References | |||||
| REF 1 | Antiviral agents active against influenza A viruses. Nat Rev Drug Discov. 2006 Dec;5(12):1015-25. | ||||
| REF 2 | PA subunit of RNA polymerase as a promising target for anti-influenza virus agents. Antiviral Res. 2008 Jun;78(3):194-201. Epub 2008 Jan 17. | ||||
| REF 3 | Activity of T-705 in a hamster model of yellow fever virus infection in comparison with that of a chemically related compound, T-1106. Antimicrob Agents Chemother. 2009 Jan;53(1):202-9. Epub 2008 Oct 27. | ||||
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