Drug Information
Drug General Information | |||||
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Drug ID |
D0A4NO
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Former ID |
DNC014008
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Drug Name |
L-162313
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Drug Type |
Small molecular drug
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Indication | Discovery agent | Investigative | [540558] | ||
Structure |
Download2D MOL |
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Formula |
C30H38N4O4S2
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InChI |
InChI=1S/C30H38N4O4S2/c1-7-9-14-38-30(35)33-40(36,37)29-25(17-24(39-29)15-19(3)4)23-12-10-22(11-13-23)18-34-26(8-2)32-27-20(5)16-21(6)31-28(27)34/h10-13,16-17,19H,7-9,14-15,18H2,1-6H3,(H,33,35)
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InChIKey |
RINPELQWLUGERM-UHFFFAOYSA-N
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PubChem Compound ID | |||||
PubChem Substance ID |
11111368, 11646401, 14911428, 17405258, 24278791, 43223692, 47720610, 50106511, 50106512, 53777803, 57264287, 80565157, 85231107, 90340748, 92304142, 103216664, 103979543, 114637026, 121361659, 124749924, 124880528, 129134295, 134351213, 135298187, 162247851, 163564651, 178100764, 234569739, 242177890, 252341892, 252559370
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Target and Pathway | |||||
Target(s) | Type-2 angiotensin II receptor | Target Info | Inhibitor | [530937] | |
Type-1 angiotensin II receptor | Target Info | Inhibitor | [529578] | ||
NetPath Pathway | TGF_beta_Receptor Signaling Pathway | ||||
Pathway Interaction Database | Arf6 trafficking events | ||||
Arf6 signaling events | |||||
Angiopoietin receptor Tie2-mediated signaling | |||||
PathWhiz Pathway | Angiotensin Metabolism | ||||
Muscle/Heart Contraction | |||||
References | |||||
Ref 529578 | Bioorg Med Chem. 2008 Jul 15;16(14):6841-9. Epub 2008 Jul 1.Selective angiotensin II AT2 receptor agonists: Benzamide structure-activity relationships. | ||||
Ref 530937 | Bioorg Med Chem. 2010 Jun 15;18(12):4570-90. Epub 2010 Apr 9.Selective angiotensin II AT(2) receptor agonists with reduced CYP 450 inhibition. |
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