Drug Information

Drug General Information
Drug ID
D0A4FU
Former ID
DNC010896
Drug Name
1-(2-allylphenoxy)-3-morpholinopropan-2-ol
Drug Type
Small molecular drug
Indication Discovery agent Investigative [530883]
Structure
Download
2D MOL

3D MOL
Formula
C16H23NO3
Canonical SMILES
C=CCC1=CC=CC=C1OCC(CN2CCOCC2)O
InChI
1S/C16H23NO3/c1-2-5-14-6-3-4-7-16(14)20-13-15(18)12-17-8-10-19-11-9-17/h2-4,6-7,15,18H,1,5,8-13H2
InChIKey
BKDPODVOOWQEGE-UHFFFAOYSA-N
PubChem Compound ID
2769774
Target and Pathway
Target(s) Beta-2 adrenergic receptor Target Info Inhibitor [530883]
Beta-1 adrenergic receptor Target Info Inhibitor [530883]
Beta-3 adrenergic receptor Target Info Inhibitor [530883]
KEGG Pathway Calcium signaling pathway
cGMP-PKG signaling pathway
cAMP signaling pathway
Neuroactive ligand-receptor interaction
Endocytosis
Adrenergic signaling in cardiomyocytes
Salivary secretionhsa04020:Calcium signaling pathway
Gap junction
Salivary secretion
Dilated cardiomyopathyhsa04020:Calcium signaling pathway
NetPath Pathway TCR Signaling Pathway
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
Beta2 adrenergic receptor signaling pathwayP00026:Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
Beta1 adrenergic receptor signaling pathwayP00026:Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
Beta3 adrenergic receptor signaling pathway
Pathway Interaction Database Arf6 trafficking events
Arf6 signaling events
PathWhiz Pathway Muscle/Heart Contraction
Reactome Adrenoceptors
G alpha (s) signalling eventsR-HSA-390696:Adrenoceptors
G alpha (s) signalling events
WikiPathways Monoamine GPCRs
Calcium Regulation in the Cardiac Cell
GPCRs, Class A Rhodopsin-like
Vitamin D Receptor Pathway
GPCR ligand binding
GPCR downstream signaling
GPCRs, OtherWP58:Monoamine GPCRs
Endothelin Pathways
GPCR downstream signalingWP58:Monoamine GPCRs
References
Ref 530883Bioorg Med Chem Lett. 2010 Jun 1;20(11):3399-404. Epub 2010 Apr 9.A vHTS approach for the identification of beta-adrenoceptor ligands.
Ref 530883Bioorg Med Chem Lett. 2010 Jun 1;20(11):3399-404. Epub 2010 Apr 9.A vHTS approach for the identification of beta-adrenoceptor ligands.

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