Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D08YUP
|
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| Former ID |
DNC012751
|
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| Drug Name |
SB-213698
|
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| Synonyms |
TAN-67
|
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| Indication | Discovery agent | Terminated | [546084] | ||
| Structure |
|
Download2D MOL |
|||
| Canonical SMILES |
CN1CCC2(CC3=NC4=CC=CC=C4C=C3CC2C1)C5=CC(=CC=C5)O
|
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| InChI |
1S/C23H24N2O/c1-25-10-9-23(18-6-4-7-20(26)13-18)14-22-17(12-19(23)15-25)11-16-5-2-3-8-21(16)24-22/h2-8,11,13,19,26H,9-10,12,14-15H2,1H3/t19-,23+/m1/s1
|
||||
| InChIKey |
LEPBHAAYNPPRRA-XXBNENTESA-N
|
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| Target and Pathway | |||||
| Target(s) | Mu-type opioid receptor | Target Info | Inhibitor | [530073] | |
| Kappa-type opioid receptor | Target Info | Inhibitor | [530073] | ||
| Delta-type opioid receptor | Target Info | Inhibitor | [530073] | ||
| NetPath Pathway | TCR Signaling Pathway | ||||
| PANTHER Pathway | Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | ||||
| Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway | |||||
| Enkephalin releaseP00026:Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | |||||
| Opioid prodynorphin pathwayP00026:Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | |||||
| Enkephalin release | |||||
| Opioid proenkephalin pathway | |||||
| Opioid proopiomelanocortin pathway | |||||
| Pathway Interaction Database | IL4-mediated signaling events | ||||
| References | |||||
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