Drug Information
Drug General Information | |||||
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Drug ID |
D08PKR
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Former ID |
DNC004476
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Drug Name |
6-Imidazol-1-yl-isoquinoline
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Synonyms |
6-(1H-imidazol-1-yl)isoquinoline
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Drug Type |
Small molecular drug
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Indication | Discovery agent | Investigative | [525760] | ||
Structure |
Download2D MOL |
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Formula |
C12H9N3
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Canonical SMILES |
C1=CC2=C(C=CN=C2)C=C1N3C=CN=C3
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InChI |
1S/C12H9N3/c1-2-12(15-6-5-14-9-15)7-10-3-4-13-8-11(1)10/h1-9H
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InChIKey |
YACWDKFXWATANA-UHFFFAOYSA-N
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PubChem Compound ID | |||||
Target and Pathway | |||||
Target(s) | Cytochrome P450 19 | Target Info | Inhibitor | [529860] | |
Thromboxane-A synthase | Target Info | Inhibitor | [525760] | ||
NetPath Pathway | FSH Signaling Pathway | ||||
PANTHER Pathway | Androgen/estrogene/progesterone biosynthesis | ||||
PathWhiz Pathway | Androgen and Estrogen MetabolismPW000044:Arachidonic Acid Metabolism | ||||
Reactome | Endogenous sterols | ||||
WikiPathways | Metapathway biotransformation | ||||
Tryptophan metabolism | |||||
Oxidation by Cytochrome P450 | |||||
Ovarian Infertility Genes | |||||
Metabolism of steroid hormones and vitamin D | |||||
FSH signaling pathway | |||||
Integrated Breast Cancer Pathway | |||||
Phase 1 - Functionalization of compoundsWP98:Prostaglandin Synthesis and Regulation | |||||
Arachidonic acid metabolism | |||||
Phase 1 - Functionalization of compounds | |||||
Eicosanoid Synthesis | |||||
References | |||||
Ref 525760 | J Med Chem. 2000 May 4;43(9):1841-51.1-imidazolyl(alkyl)-substituted di- and tetrahydroquinolines and analogues: syntheses and evaluation of dual inhibitors of thromboxane A(2) synthase and aromatase. | ||||
Ref 529860 | J Med Chem. 2009 Jan 8;52(1):143-50.Fast three dimensional pharmacophore virtual screening of new potent non-steroid aromatase inhibitors. |
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