Drug Information

Drug General Information
Drug ID
D08LLM
Former ID
DIB012009
Drug Name
NS-8
Drug Type
Small molecular drug
Indication Urinary incontinence [ICD9: 788.3; ICD10:N39.3, N39.4, R32] Phase 1 [551445]
Company
Nippon Shinyaku Co Ltd
Structure
Download
2D MOL

3D MOL
Formula
C12H10FN3
Canonical SMILES
c1([nH]c(c(c1C)C#N)N)c1c(F)cccc1
CAS Number
CAS 186033-14-7
PubChem Compound ID
10176749
Target and Pathway
Target(s) Potassium channel Target Info Agonist [532744]
References
Ref 551445Clinical pipeline report, company report or official report of Nippon Shinyaku Co Ltd.
Ref 532744Stimulation of large-conductance calcium-activated potassium channels inhibits neurogenic contraction of human bladder from patients with urinary symptoms and reverses acetic acid-induced bladder hyperactivity in rats. Eur J Pharmacol. 2014 Jul 15;735:68-76.

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