| Drug General Information |
| Drug ID |
D07KZA
|
| Former ID |
DNC002570
|
| Drug Name |
2-(N-Morpholino)-Ethanesulfonic Acid
|
| Drug Type |
Small molecular drug
|
| Indication |
Discovery agent
|
Investigative |
[1]
|
|---|
| Structure |
|
Download
2D MOL
3D MOL
|
| Formula |
C6H11NO5S
|
| Canonical SMILES |
C1COC(=O)CN1CCS(=O)(=O)O
|
| InChI |
1S/C6H11NO5S/c8-6-5-7(1-3-12-6)2-4-13(9,10)11/h1-5H2,(H,9,10,11)
|
| InChIKey |
WZURJOAQBDIKCN-UHFFFAOYSA-N
|
| PubChem Compound ID |
|
| PubChem Substance ID |
|
| Target and Pathway |
| Target(s) |
Corticosteroid 11-beta-dehydrogenase, isozyme 1 |
Target Info |
Inhibitor |
[1]
|
|---|
| Beta-lactamase |
Target Info |
Inhibitor |
[1]
|
| Flavohemoglobin |
Target Info |
Inhibitor |
[1]
|
| Dihydrofolate reductase |
Target Info |
Inhibitor |
[1]
|
| Acetylcholinesterase |
Target Info |
Inhibitor |
[1]
|
| Glucosamine-6-phosphate synthase |
Target Info |
Inhibitor |
[1]
|
| Chymase |
Target Info |
Inhibitor |
[1]
|
| Cholinesterase |
Target Info |
Inhibitor |
[1]
|
|
KEGG Pathway
|
Steroid hormone biosynthesis
|
|
Metabolism of xenobiotics by cytochrome P450
|
|
Metabolic pathways
|
|
Chemical carcinogenesishsa00564:Glycerophospholipid metabolism
|
|
Cholinergic synapsehsa04614:Renin-angiotensin system
|
|
NetPath Pathway
|
IL1 Signaling Pathway
|
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FSH Signaling Pathway
|
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PANTHER Pathway
|
Muscarinic acetylcholine receptor 1 and 3 signaling pathway
|
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Muscarinic acetylcholine receptor 2 and 4 signaling pathway
|
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Nicotinic acetylcholine receptor signaling pathwayP00042:Muscarinic acetylcholine receptor 1 and 3 signaling pathway
|
|
Nicotinic acetylcholine receptor signaling pathway
|
|
Pathway Interaction Database
|
ATF-2 transcription factor network
|
|
PathWhiz Pathway
|
SteroidogenesisPW000024:Folate Metabolism
|
|
Pterine BiosynthesisPW000048:Phospholipid Biosynthesis
|
|
Reactome
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Glucocorticoid biosynthesisR-HSA-113510:E2F mediated regulation of DNA replication
|
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Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
|
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Metabolism of folate and pterines
|
|
G1/S-Specific TranscriptionR-HSA-1592389:Activation of Matrix Metalloproteinases
|
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Metabolism of Angiotensinogen to Angiotensins
|
|
WikiPathways
|
Prostaglandin Synthesis and Regulation
|
|
Metabolism of steroid hormones and vitamin D
|
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Glucocorticoid & Mineralcorticoid MetabolismWP727:Monoamine Transport
|
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Biogenic Amine Synthesis
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Acetylcholine Synthesis
|
|
Integrated Pancreatic Cancer PathwayWP554:ACE Inhibitor Pathway
|
|
Metabolism of Angiotensinogen to AngiotensinsWP229:Irinotecan Pathway
|
| References |
| REF 1 | How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. |
|---|
