| Drug General Information |
| Drug ID |
D07AAK
|
| Former ID |
DNC004917
|
| Drug Name |
M6G thiosaccharide analogue
|
| Indication |
Discovery agent
|
Investigative |
[1]
|
|---|
| Structure |
|
Download
2D MOL
3D MOL
|
| Target and Pathway |
| Target(s) |
Delta-type opioid receptor |
Target Info |
Inhibitor |
[1]
|
|---|
| Kappa-type opioid receptor |
Target Info |
Inhibitor |
[1]
|
| Mu-type opioid receptor |
Target Info |
Inhibitor |
[1]
|
|
KEGG Pathway
|
cGMP-PKG signaling pathway
|
|
Sphingolipid signaling pathway
|
|
Neuroactive ligand-receptor interactionhsa04080:Neuroactive ligand-receptor interactionhsa04080:Neuroactive ligand-receptor interaction
|
|
Estrogen signaling pathway
|
|
Morphine addiction
|
|
NetPath Pathway
|
TCR Signaling Pathway
|
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PANTHER Pathway
|
Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
|
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Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
|
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Enkephalin release
|
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Opioid proenkephalin pathway
|
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Opioid proopiomelanocortin pathwayP00026:Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
|
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Opioid prodynorphin pathwayP00026:Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
|
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Pathway Interaction Database
|
IL4-mediated signaling events
|
|
Reactome
|
Peptide ligand-binding receptors
|
|
G alpha (i) signalling eventsR-HSA-375276:Peptide ligand-binding receptors
|
|
G alpha (i) signalling events
|
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WikiPathways
|
GPCRs, Class A Rhodopsin-like
|
|
Peptide GPCRs
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GPCR ligand binding
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GPCR downstream signalingWP455:GPCRs, Class A Rhodopsin-like
|
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GPCR downstream signalingWP69:TCR Signaling Pathway
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Opioid Signalling
|
|
GPCR downstream signaling
|
| References |
| REF 1 | Bioorg Med Chem Lett. 2005 Mar 15;15(6):1583-6.Synthesis and in vitro biological evaluation of a carbon glycoside analogue of morphine-6-glucuronide. |
|---|
