Drug Information
Drug General Information | |||||
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Drug ID |
D06UDG
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Former ID |
DAP000363
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Drug Name |
Valsartan
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Synonyms |
Diovan; Kalpress; Miten; Nisis; Provas; Tareg; Vals; Valsarran; Walsartan; Aventis brand of valsartan; CEPA brand of valsartan; Esteve brand of valsartan; Lacer brand of valsartan; Novartis brand of valsartan; Sanol brand of valsartan; Schwarz brand of valsartan; CGP 48933; CGP-48933; Diovan (TN); Diovan, Valsartan; Valsartan [USAN:INN]; Valtan (TN); Valzaar (TN); Valsartan (JAN/USAN/INN); N-(p-(o-1H-Tetrazol-5-ylphenyl)benzyl)-N-valeryl-L-valine; N-valeryl-N-((2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl)valine; N-pentanoyl-N-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-L-valine; N-pentanoyl-N-{[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl}-L-valine; N-(1-oxopentyl)-N-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-L-valine; L-Valine, N-(1-oxopentyl)-N-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-(9CI); (2S)-3-methyl-2-[pentanoyl-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]amino]butanoic acid; (S)-N-valeryl-N-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]-methyl}-valine; (s)-2-(n-((2'-(1h-tetrazol-5-yl)biphenyl-4-yl)methyl)pentanamido)-3-methylbutanoic acid
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Drug Type |
Small molecular drug
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Therapeutic Class |
Antihypertensive Agents
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Company |
Norvatis Phamaceuticals Corporation
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Structure |
Download2D MOL |
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Formula |
C24H29N5O3
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InChI |
InChI=1S/C24H29N5O3/c1-4-5-10-21(30)29(22(16(2)3)24(31)32)15-17-11-13-18(14-12-17)19-8-6-7-9-20(19)23-25-27-28-26-23/h6-9,11-14,16,22H,4-5,10,15H2,1-3H3,(H,31,32)(H,25,26,27,28)/t22-/m0/s1
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InChIKey |
ACWBQPMHZXGDFX-QFIPXVFZSA-N
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CAS Number |
CAS 137862-53-4
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PubChem Compound ID | |||||
PubChem Substance ID |
7847466, 11066615, 11364700, 11367262, 11369824, 11373100, 11374217, 11377988, 11484996, 11488936, 11491646, 11492564, 11495610, 14856825, 14881173, 26612829, 26719825, 43118184, 46386599, 46509000, 46530915, 47499543, 48393917, 49681716, 49830875, 50062253, 50467452, 53787275, 57314146, 81093312, 85788951, 90452226, 92124805, 92308052, 92308462, 92711441, 93166503, 99228303, 103292815, 103979540, 104253413, 104321799, 117541337, 117664453, 119526522, 123055291, 124659015, 124757534, 124800101, 125164338
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ChEBI ID |
ChEBI:9927
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SuperDrug ATC ID |
C09CA03
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SuperDrug CAS ID |
cas=137862534
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Target and Pathway | |||||
Target(s) | Type-1 angiotensin II receptor | Target Info | Antagonist | [535660], [537449] | |
NetPath Pathway | TGF_beta_Receptor Signaling Pathway | ||||
Pathway Interaction Database | Arf6 trafficking events | ||||
Arf6 signaling events | |||||
Angiopoietin receptor Tie2-mediated signaling | |||||
PathWhiz Pathway | Angiotensin Metabolism | ||||
Muscle/Heart Contraction | |||||
References | |||||
Ref 536361 | Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77. Epub 2007 Feb 20. | ||||
Ref 540559 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 3937). |
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