Drug Information
Drug General Information | |||||
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Drug ID |
D06TZT
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Former ID |
DIB010437
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Drug Name |
RIPISARTAN
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Synonyms |
Ripisartan < Prop INN >; UP-269-6; 5-Methyl-7-propyl-8-[2'-(1H-tetrazol-5-yl)biphenyl-4-ylmethyl]-1,2,4-triazolo[1,5-c]pyrimidin-2(3H)-one
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Drug Type |
Small molecular drug
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Indication | Hypertension [ICD9: 401; ICD10:I10-I16] | Discontinued in Phase 2 | [545748] | ||
Structure |
Download2D MOL |
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Formula |
C23H22N8O
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Canonical SMILES |
CCCc1nc(C)n2nc(O)nc2c1Cc3ccc(cc3)c4ccccc4c5nn[nH]n5
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InChI |
1S/C23H22N8O/c1-3-6-20-19(22-25-23(32)28-31(22)14(2)24-20)13-15-9-11-16(12-10-15)17-7-4-5-8-18(17)21-26-29-30-27-21/h4-5,7-12H,3,6,13H2,1-2H3,(H,28,32)(H,26,27,29,30)
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InChIKey |
OLJAPHMBAMBVKL-UHFFFAOYSA-N
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CAS Number |
CAS 148504-51-2
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PubChem Compound ID | |||||
Target and Pathway | |||||
Target(s) | Type-1 angiotensin II receptor | Target Info | Antagonist | [533666], [551871] | |
NetPath Pathway | TGF_beta_Receptor Signaling Pathway | ||||
Pathway Interaction Database | Arf6 trafficking events | ||||
Arf6 signaling events | |||||
Angiopoietin receptor Tie2-mediated signaling | |||||
PathWhiz Pathway | Angiotensin Metabolism | ||||
Muscle/Heart Contraction | |||||
References |
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