Drug Information
Drug General Information | |||||
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Drug ID |
D06FES
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Former ID |
DAP000177
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Drug Name |
Doxepin
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Synonyms |
Cidoxepin; Cidoxepina; Cidoxepinum; Doxepina; Doxepine; Doxepinum; Quitaxon; Sinequan; Triadapin; Zonalon; Cidoxepin [INN]; Doxepin Hydrochloride; Doxepin [USAN]; MF 10; MOLI001594; Adapine (TN); Aponal (TN); Cis-doxepin; Deptran (TN); Doxepin (INN); Doxepin, Hydrochloride; Doxepina [INN-Spanish]; Doxepinum [INN-Latin]; Sinequan (TN); Sinquan (TN); Xepin (TN); Zonalon (TN); Doxepin (Z)-isomer; N,N-Dimethyldibenz(b,e)oxepin-delta(11(6H),gamma)-propylamine; Cis-N-(3-(6H-Dibenz(b,e)oxepin-11-yliden)propyl)-N,N-dimethylamin; (3E)-3-(6H-benzo[c][1]benzoxepin-11-ylidene)-N,N-dimethylpropan-1-amine; (3E)-3-dibenzo[b,e]oxepin-11(6H)-ylidene-N,N-dimethylpropan-1-amine; (3Z)-3-(6H-benzo[c][1]benzoxepin-11-ylidene)-N,N-di(methyl)propan-1-amine; (3Z)-3-(6H-benzo[c][1]benzoxepin-11-ylidene)-N,N-dimethylpropan-1-amine; (3Z)-3-dibenzo[b,e]oxepin-11(6H)-ylidene-N,N-dimethylpropan-1-amine; (Z)-Doxepin; 11-(3-(Dimethylamino)propylidene)-6H-dibenz(b,e)oxepine; 11-(3-Dimethylamino-propyliden)-6,11-dihydro-dibenz(b,e)oxipin; 11-(3-Dimethylaminopropylidene)-6,11-dihydrodibenz(b,e)oxipin; 3-(6H-benzo[c][1]benzoxepin-11-ylidene)-N,N-dimethylpropan-1-amine; 3-Dibenz[b,e]oxepin-11(6H)-ylidene-N,N-dimethyl-1-propanamine; 3-dibenzo[b,e]oxepin-11(6H)-ylidene-N,N-dimethylpropan-1-amine
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Drug Type |
Small molecular drug
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Therapeutic Class |
Antidepressants
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Company |
Pfizer Pharmaceuticals
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Structure |
Download2D MOL |
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Formula |
C19H21NO
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InChI |
InChI=1S/C19H21NO/c1-20(2)13-7-11-17-16-9-4-3-8-15(16)14-21-19-12-6-5-10-18(17)19/h3-6,8-12H,7,13-14H2,1-2H3/b17-11+
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InChIKey |
ODQWQRRAPPTVAG-GZTJUZNOSA-N
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CAS Number |
CAS 1668-19-5
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PubChem Compound ID | |||||
PubChem Substance ID |
9185, 7979128, 9276661, 11111071, 11111072, 11113537, 15222194, 47349355, 48094536, 48169369, 48243362, 48243363, 49698411, 49962689, 50064724, 50111016, 53787313, 57408485, 74600407, 85209421, 85787476, 85787555, 90341830, 96024571, 104098315, 104171145, 109839956, 123090162, 124361053, 124749633, 126651546, 134337497, 134980709, 135650208, 137001419, 142365241, 160964476, 163423735, 163639170, 163853816, 164786701, 172883005, 175270523, 176224908, 176267053, 178100785, 179116660, 184548423, 194690521, 196105693
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ChEBI ID |
ChEBI:4710
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SuperDrug ATC ID |
N06AA12
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SuperDrug CAS ID |
cas=001668195
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Target and Pathway | |||||
Target(s) | Histamine H1 receptor | Target Info | Inhibitor | [536469] | |
PANTHER Pathway | Histamine H1 receptor mediated signaling pathway | ||||
References | |||||
Ref 536306 | Emerging treatments for depression. Expert Opin Pharmacother. 2006 Dec;7(17):2323-39. | ||||
Ref 538737 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1225). |
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