Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D06ALC
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| Former ID |
DNC014243
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| Drug Name |
Lithospermic acid
|
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent | Investigative | [530340] | ||
| Structure |
|
Download2D MOL |
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| Formula |
C27H22O12
|
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| Canonical SMILES |
C1=CC(=C(C=C1CC(C(=O)O)OC(=O)C=CC2=C3C(C(OC3=C(C=C2)O)C<br />4=CC(=C(C=C4)O)O)C(=O)O)O)O
|
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| InChI |
1S/C27H22O12/c28-15-5-1-12(9-18(15)31)10-20(26(34)35)38-21(33)8-4-13-2-7-17(30)25-22(13)23(27(36)37)24(39-25)14-3-6-16(29)19(32)11-14/h1-9,11,20,23-24,28-32H,10H2,(H,34,35)(H,36,37)/b8-4+/t20-,23+,24-/m1/s1
|
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| InChIKey |
UJZQBMQZMKFSRV-RGKBJLTCSA-N
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | 72 kDa type IV collagenase | Target Info | Inhibitor | [530340] | |
| PANTHER Pathway | Alzheimer disease-presenilin pathway | ||||
| Pathway Interaction Database | LPA receptor mediated events | ||||
| Plasma membrane estrogen receptor signaling | |||||
| Osteopontin-mediated events | |||||
| Validated transcriptional targets of AP1 family members Fra1 and Fra2 | |||||
| Angiopoietin receptor Tie2-mediated signaling | |||||
| Direct p53 effectors | |||||
| amb2 Integrin signaling | |||||
| ATF-2 transcription factor network | |||||
| FOXM1 transcription factor network | |||||
| Regulation of nuclear beta catenin signaling and target gene transcription | |||||
| Syndecan-2-mediated signaling events | |||||
| References | |||||
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