Drug Information
Drug General Information | |||||
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Drug ID |
D05TIB
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Former ID |
DAP000342
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Drug Name |
Trospium
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Synonyms |
Spasmex; Spasmoplex; Trosec; Trospium chloride; IP-631; Regurin (TN); Sanctura (TN); Spasmex (TN); Spasmoplex (TN); Trosec (TN); Trospium chloride (JAN/USAN/INN); Spiro(8-azoniabicyclo(3.2.1)octane-8,1'-pyrrolidinium), 3-hydroxy-, chloride, benzilate; Spiro[8-azoniabicyclo[3.2.1]octane-8,1'-azolidin-1-ium]-3-yl 2-hydroxy-2,2-diphenylacetate; Spiro[8-azoniabicyclo[3.2.1]octane-8,1'-azolidin-1-ium]-3-yl 2-hydroxy-2,2-diphenylacetate chloride; 3-Hydroxyspiro(8-azoniabicyclo(3.2.1)octane-8,1'-pyrrolidinium) chloride benzilate; 6,10-Ethano-5-azoniaspiro(4.5)decan-8-ol, chloride, benzilate; 8-Benziloyloxy-6,10-ethano-5-azoniaspiro(4.5)decane chloride
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Drug Type |
Small molecular drug
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Therapeutic Class |
Parasympatholytics
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Company |
Allergan Pharmaceuticals
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Structure |
Download2D MOL |
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Formula |
C25H30NO3+
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InChI |
InChI=1S/C25H30NO3/c27-24(25(28,19-9-3-1-4-10-19)20-11-5-2-6-12-20)29-23-17-21-13-14-22(18-23)26(21)15-7-8-16-26/h1-6,9-12,21-23,28H,7-8,13-18H2/q+1
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InChIKey |
OYYDSUSKLWTMMQ-UHFFFAOYSA-N
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CAS Number |
CAS 10405-02-4
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PubChem Compound ID | |||||
PubChem Substance ID | |||||
SuperDrug ATC ID |
G04BD09
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SuperDrug CAS ID |
cas=010405024
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Target and Pathway | |||||
Target(s) | Muscarinic acetylcholine receptor M5 | Target Info | Antagonist | [536284] | |
References | |||||
Ref 527466 | 2004 approvals: the demise of the blockbuster. Nat Rev Drug Discov. 2005 Feb;4(2):93-4. | ||||
Ref 528278 | Trospium chloride: the European experience. Expert Opin Pharmacother. 2006 Jul;7(10):1373-80. | ||||
Ref 538569 | FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (NDA) 021595. | ||||
Ref 542503 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7480). | ||||
Ref 551871 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015 |
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