Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D05LSB
|
||||
| Former ID |
DIB002886
|
||||
| Drug Name |
COX-2 inhibitors
|
||||
| Synonyms |
Anti-inflammatories, FAES Farma; COX-2 inhibitors, FAES Farma; Cyclooxygenase-2 inhibitor, FAES Farma
|
||||
| Indication | Inflammatory disease [ICD9: 140-229, 147, 173, 573.3, 710-719; ICD10:C11, C44, K75.9, M00-M25] | Investigative | [552034] | ||
| Company |
FAES Farma SA
|
||||
| Structure |
|
Download2D MOL |
|||
| Canonical SMILES |
O=S(=O)(c1ccc(c2nc(cc(C(F)(F)F)n2)NCc2ccccc2)cc1)C
|
||||
| Target and Pathway | |||||
| Target(s) | Prostaglandin G/H synthase 2 | Target Info | Inhibitor | [543413] | |
| KEGG Pathway | Arachidonic acid metabolism | ||||
| Metabolic pathways | |||||
| NF-kappa B signaling pathway | |||||
| VEGF signaling pathway | |||||
| TNF signaling pathway | |||||
| Retrograde endocannabinoid signaling | |||||
| Serotonergic synapse | |||||
| Ovarian steroidogenesis | |||||
| Oxytocin signaling pathway | |||||
| Regulation of lipolysis in adipocytes | |||||
| Leishmaniasis | |||||
| Pathways in cancer | |||||
| Chemical carcinogenesis | |||||
| MicroRNAs in cancer | |||||
| Small cell lung cancer | |||||
| PathWhiz Pathway | Arachidonic Acid Metabolism | ||||
| References | |||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.