Drug Information
Drug General Information | |||||
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Drug ID |
D05ICS
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Former ID |
DIB004891
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Drug Name |
ProSavin
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Synonyms |
Dopamine synthesis pathway gene therapy (Parkinson's disease), Oxford BioMedica
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Indication | Parkinson's disease [ICD9: 332; ICD10:G20] | Phase 1/2 | [524296] | ||
Company |
Oxford BioMedica plc
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Target and Pathway | |||||
Target(s) | GTP cyclohydrolase I | Target Info | Modulator | [551478] | |
Aromatic-L-amino-acid decarboxylase | Target Info | Modulator | [551478] | ||
Tyrosine 3-monooxygenase | Target Info | Modulator | [551478] | ||
WikiPathways | SIDS Susceptibility Pathways | ||||
Biogenic Amine Synthesis | |||||
Tryptophan metabolism | |||||
Dopaminergic Neurogenesis | |||||
Metabolism of amino acids and derivatives | |||||
Dopamine metabolism | |||||
Parkinsons Disease Pathway | |||||
Nicotine Activity on Dopaminergic NeuronsWP727:Monoamine Transport | |||||
Nicotine Activity on Dopaminergic Neurons | |||||
References |
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