Drug Information
Drug General Information | |||||
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Drug ID |
D05CKR
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Former ID |
DIB010213
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Drug Name |
Nabumetone
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Synonyms |
NNB-001; NNB-004; NNB-005; Nabumetone (oral); Nabumetone (oral), Nobex; 6-MNA (oral), Nobex
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Drug Type |
Small molecular drug
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Company |
Nobex Corp
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Structure |
Download2D MOL |
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Formula |
C15H16O2
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InChIKey |
BLXXJMDCKKHMKV-UHFFFAOYSA-N
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PubChem Compound ID | |||||
PubChem Substance ID |
866759, 5089100, 7847491, 7980058, 8139968, 8150030, 8152727, 11112767, 11336025, 11361264, 11364380, 11366942, 11369504, 11373826, 11377666, 11462236, 11466937, 11468057, 11485833, 11486693, 11489785, 11491989, 11495300, 12012677, 15196152, 24897772, 26612514, 26679665, 26748824, 26748825, 29223506, 46507729, 47216826, 47515367, 47662339, 47736536, 47885464, 48035181, 49698816, 49896758, 53786809, 56364587, 56422157, 57322259, 57654458, 80932204, 85087976, 85787391, 92124694, 92125724
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Target and Pathway | |||||
Target(s) | Prostaglandin G/H synthase 2 | Target Info | Inhibitor | [526187] | |
KEGG Pathway | Arachidonic acid metabolism | ||||
Metabolic pathways | |||||
NF-kappa B signaling pathway | |||||
VEGF signaling pathway | |||||
TNF signaling pathway | |||||
Retrograde endocannabinoid signaling | |||||
Serotonergic synapse | |||||
Ovarian steroidogenesis | |||||
Oxytocin signaling pathway | |||||
Regulation of lipolysis in adipocytes | |||||
Leishmaniasis | |||||
Pathways in cancer | |||||
Chemical carcinogenesis | |||||
MicroRNAs in cancer | |||||
Small cell lung cancer | |||||
PathWhiz Pathway | Arachidonic Acid Metabolism | ||||
References | |||||
Ref 523116 | ClinicalTrials.gov (NCT01164826) Bioequivalence Study of Nabumetone 750 mg Tablets of Dr. Reddy's Under Fed Conditions. U.S. National Institutes of Health. | ||||
Ref 542262 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7245). |
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