Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D04JCK
|
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| Former ID |
DNC000631
|
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| Drug Name |
Etorphine
|
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| Drug Type |
Small molecular drug
|
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| Indication | Discovery agent | Investigative | [538999] | ||
| Structure |
|
Download2D MOL |
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| Formula |
C25H33NO4
|
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| InChI |
InChI=1S/C25H33NO4/c1-5-8-22(2,28)17-14-23-9-10-25(17,29-4)21-24(23)11-12-26(3)18(23)13-15-6-7-16(27)20(30-21)19(15)24/h6-7,9-10,17-18,21,27-28H,5,8,11-14H2,1-4H3
|
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| InChIKey |
CAHCBJPUTCKATP-UHFFFAOYSA-N
|
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| CAS Number |
CAS 13764-49-3
|
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| PubChem Compound ID | |||||
| PubChem Substance ID | |||||
| ChEBI ID |
ChEBI:4912
|
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| Target and Pathway | |||||
| Target(s) | Delta-type opioid receptor | Target Info | Agonist | [535235] | |
| Mu-type opioid receptor | Target Info | Agonist | [535313] | ||
| NetPath Pathway | TCR Signaling Pathway | ||||
| PANTHER Pathway | Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | ||||
| Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway | |||||
| Enkephalin release | |||||
| Opioid proenkephalin pathway | |||||
| Opioid proopiomelanocortin pathwayP00026:Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | |||||
| Pathway Interaction Database | IL4-mediated signaling events | ||||
| References | |||||
| Ref 535235 | Agonist-, antagonist-, and inverse agonist-regulated trafficking of the delta-opioid receptor correlates with, but does not require, G protein activation. J Pharmacol Exp Ther. 2001 Sep;298(3):1015-20. | ||||
| Ref 535313 | Internalization of mu-opioid receptors produced by etorphine in the rat locus coeruleus. Neuroscience. 2001;108(3):467-77. | ||||
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