Drug Information

Drug General Information
Drug ID
D04IEW
Former ID
DNC007171
Drug Name
GINKGOLIDE A
Drug Type
Small molecular drug
Indication Discovery agent Investigative [539171]
Structure
Download
2D MOL

3D MOL
Formula
C20H24O9
InChI
InChI=1S/C20H24O9/c1-7-12(22)26-10-6-17-9-5-8(16(2,3)4)18(17)11(21)13(23)28-15(18)29-20(17,14(24)27-9)19(7,10)25/h7-11,15,21,25H,5-6H2,1-4H3/t7-,8+,9-,10+,11?,15+,17?,18?,19-,20-/m1/s1
InChIKey
FPUXKXIZEIDQKW-MSAFPSTDSA-N
CAS Number
CAS 15291-75-5
PubChem Compound ID
441293
PubChem Substance ID
9803, 74382527, 135652684, 135692376, 137140593, 162038209, 164810628, 179316256, 223439818, 226675615
Target and Pathway
Target(s) Glycine receptor Target Info Inhibitor [528727]
Glycine receptor alpha-1 chain Target Info Inhibitor [528727]
KEGG Pathway Neuroactive ligand-receptor interactionhsa04080:Neuroactive ligand-receptor interaction
Reactome Ligand-gated ion channel transportR-HSA-975298:Ligand-gated ion channel transport
WikiPathways Iron uptake and transport
References
Ref 539171(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1861).
Ref 528727J Med Chem. 2007 Apr 5;50(7):1610-7. Epub 2007 Mar 13.Probing the pharmacophore of ginkgolides as glycine receptor antagonists.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.