Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D03YMX
|
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| Former ID |
DNC005188
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| Drug Name |
3,4,6-Tribromo-2-(2,4-dibromo-phenoxy)-phenol
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| Drug Type |
Small molecular drug
|
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| Indication | Discovery agent | Investigative | [1] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C12H5Br5O2
|
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| Canonical SMILES |
C1=CC(=C(C=C1Br)Br)OC2=C(C(=CC(=C2Br)Br)Br)O
|
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| InChI |
1S/C12H5Br5O2/c13-5-1-2-9(6(14)3-5)19-12-10(17)7(15)4-8(16)11(12)18/h1-4,18H
|
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| InChIKey |
FAGFPLJEMPQMRV-UHFFFAOYSA-N
|
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Arachidonate 12-lipoxygenase, 12S-type | Target Info | Inhibitor | [1] | |
| Arachidonate 15-lipoxygenase | Target Info | Inhibitor | [1] | ||
| BioCyc Pathway | Lipoxin biosynthesisPWY66-397:Resolvin D biosynthesis | ||||
| Lipoxin biosynthesis | |||||
| KEGG Pathway | Arachidonic acid metabolism | ||||
| Metabolic pathways | |||||
| Serotonergic synapse | |||||
| Inflammatory mediator regulation of TRP channelshsa00590:Arachidonic acid metabolism | |||||
| Linoleic acid metabolism | |||||
| NetPath Pathway | IL4 Signaling Pathway | ||||
| PANTHER Pathway | Inflammation mediated by chemokine and cytokine signaling pathwayP00031:Inflammation mediated by chemokine and cytokine signaling pathway | ||||
| Pathway Interaction Database | IL4-mediated signaling events | ||||
| PathWhiz Pathway | Arachidonic Acid MetabolismPW000044:Arachidonic Acid Metabolism | ||||
| WikiPathways | Arachidonic acid metabolism | ||||
| Eicosanoid SynthesisWP2650:Arachidonic acid metabolism | |||||
| Eicosanoid Synthesis | |||||
| References | |||||
| REF 1 | J Med Chem. 2004 Jul 29;47(16):4060-5.Probing the activity differences of simple and complex brominated aryl compounds against 15-soybean, 15-human, and 12-human lipoxygenase. | ||||
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