Drug Information

Drug General Information
Drug ID
D03PJU
Former ID
DNC003328
Drug Name
Carfentanil
Drug Type
Small molecular drug
Indication Discovery agent Phase 2 [524366]
Structure
Download
2D MOL

3D MOL
Formula
C24H30N2O3
Canonical SMILES
CCC(=O)N(C1=CC=CC=C1)C2(CCN(CC2)CCC3=CC=CC=C3)C(=O)OC
InChI
1S/C24H30N2O3/c1-3-22(27)26(21-12-8-5-9-13-21)24(23(28)29-2)15-18-25(19-16-24)17-14-20-10-6-4-7-11-20/h4-13H,3,14-19H2,1-2H3
InChIKey
YDSDEBIZUNNPOB-UHFFFAOYSA-N
CAS Number
CAS 59708-52-0
PubChem Compound ID
62156
PubChem Substance ID
8187910, 16847866, 22395327, 43119324, 46505501, 50015735, 57314612, 80840190, 96024451, 103224159, 103924756, 104222357, 104325105, 109614507, 117553158, 129780983, 134222605, 135020271, 137129263, 141935616, 160964782, 162630311, 164837838, 175443459, 180100818, 198942200, 226488467, 241102489, 250116464
Target and Pathway
Target(s) Delta-type opioid receptor Target Info Agonist [551406]
Kappa-type opioid receptor Target Info Agonist [551406]
Mu-type opioid receptor Target Info Agonist [551406]
KEGG Pathway cGMP-PKG signaling pathway
Sphingolipid signaling pathway
Neuroactive ligand-receptor interactionhsa04080:Neuroactive ligand-receptor interactionhsa04080:Neuroactive ligand-receptor interaction
Estrogen signaling pathway
Morphine addiction
NetPath Pathway TCR Signaling Pathway
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
Enkephalin release
Opioid proenkephalin pathway
Opioid proopiomelanocortin pathwayP00026:Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
Opioid prodynorphin pathwayP00026:Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
Pathway Interaction Database IL4-mediated signaling events
Reactome Peptide ligand-binding receptors
G alpha (i) signalling eventsR-HSA-375276:Peptide ligand-binding receptors
G alpha (i) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Peptide GPCRs
GPCR ligand binding
GPCR downstream signalingWP455:GPCRs, Class A Rhodopsin-like
GPCR downstream signalingWP69:TCR Signaling Pathway
Opioid Signalling
GPCR downstream signaling
References
Ref 524366ClinicalTrials.gov (NCT01899170) Towards Individualized Deep Brain Stimulation Treatment of Chronic Neuropathic Pain. U.S. National Institutes of Health.
Ref 551406Wax PM, Becker CE, Curry SC: Unexpected “gas” casualties in Moscow: a medical toxicology perspective. Ann Emerg Med. 2003 May;41(5):700-5.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.