Drug General Information
Drug ID
D02VBF
Former ID
DIB018012
Drug Name
BI-D1870
Drug Type
Small molecular drug
Indication Chronic lymphocytic leukaemia [ICD10:C91] Preclinical [528477]
Structure
Download
2D MOL
Formula
C19H23F2N5O2
InChI
InChI=1S/C19H23F2N5O2/c1-10(2)5-6-26-11(3)18(28)25(4)15-9-22-19(24-17(15)26)23-12-7-13(20)16(27)14(21)8-12/h7-11,27H,5-6H2,1-4H3,(H,22,23,24)
InChIKey
DTEKTGDVSARYDS-UHFFFAOYSA-N
PubChem Compound ID
PubChem Substance ID
Target and Pathway
Target(s) ribosomal protein S6 kinase, 90kDa, polypeptide 2 Target Info Inhibitor [528477]
ribosomal protein S6 kinase, 90kDa, polypeptide 1 Target Info Inhibitor [528477]
ribosomal protein S6 kinase, 90kDa, polypeptide 3 Target Info Inhibitor [528477]
ribosomal protein S6 kinase, 90kDa, polypeptide 6 Target Info Inhibitor [528477]
References
Ref 528477BI-D1870 is a specific inhibitor of the p90 RSK (ribosomal S6 kinase) isoforms in vitro and in vivo. Biochem J. 2007 Jan 1;401(1):29-38.
Ref 528477BI-D1870 is a specific inhibitor of the p90 RSK (ribosomal S6 kinase) isoforms in vitro and in vivo. Biochem J. 2007 Jan 1;401(1):29-38.

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