Drug Information
Drug General Information | |||||
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Drug ID |
D02UUR
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Former ID |
DNC008891
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Drug Name |
3-[3-(4-hydroxyphenyl)isoxazol-5-yl]phenol
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Drug Type |
Small molecular drug
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Indication | Discovery agent | Investigative | [529504] | ||
Structure |
Download2D MOL |
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Formula |
C15H11NO3
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Canonical SMILES |
C1=CC(=CC(=C1)O)C2=CC(=C3C=CC(=O)C=C3)NO2
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InChI |
1S/C15H11NO3/c17-12-6-4-10(5-7-12)14-9-15(19-16-14)11-2-1-3-13(18)8-11/h1-9,16,18H
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InChIKey |
JCAPNUWLABWVGB-UHFFFAOYSA-N
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PubChem Compound ID | |||||
Target and Pathway | |||||
Target(s) | Estradiol 17 beta-dehydrogenase 1 | Target Info | Inhibitor | [529504] | |
NetPath Pathway | FSH Signaling Pathway | ||||
PANTHER Pathway | Androgen/estrogene/progesterone biosynthesis | ||||
PathWhiz Pathway | Androgen and Estrogen Metabolism | ||||
References | |||||
Ref 529504 | Bioorg Med Chem. 2008 Jun 15;16(12):6423-35. Epub 2008 May 3.Design, synthesis and biological evaluation of bis(hydroxyphenyl) azoles as potent and selective non-steroidal inhibitors of 17beta-hydroxysteroid dehydrogenase type 1 (17beta-HSD1) for the treatment of estrogen-dependent diseases. | ||||
Ref 529504 | Bioorg Med Chem. 2008 Jun 15;16(12):6423-35. Epub 2008 May 3.Design, synthesis and biological evaluation of bis(hydroxyphenyl) azoles as potent and selective non-steroidal inhibitors of 17beta-hydroxysteroid dehydrogenase type 1 (17beta-HSD1) for the treatment of estrogen-dependent diseases. |
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