| Drug General Information |
| Drug ID |
D02TQC
|
| Former ID |
DNC003849
|
| Drug Name |
N-(5-Bromo-quinoxalin-6-yl)-guanidine
|
| Drug Type |
Small molecular drug
|
| Indication |
Discovery agent
|
Investigative |
[1]
|
|---|
| Structure |
|
Download
2D MOL
3D MOL
|
| Formula |
C9H8BrN5
|
| Canonical SMILES |
C1=CC2=NC=CN=C2C(=C1N=C(N)N)Br
|
| InChI |
1S/C9H8BrN5/c10-7-5(15-9(11)12)1-2-6-8(7)14-4-3-13-6/h1-4H,(H4,11,12,15)
|
| InChIKey |
WBGSURPVIDDDHF-UHFFFAOYSA-N
|
| PubChem Compound ID |
|
| Target and Pathway |
| Target(s) |
Alpha-1A adrenergic receptor |
Target Info |
Inhibitor |
[1]
|
|---|
| Alpha-1D adrenergic receptor |
Target Info |
Inhibitor |
[1]
|
| Alpha-1B adrenergic receptor |
Target Info |
Inhibitor |
[1]
|
|
KEGG Pathway
|
Calcium signaling pathway
|
|
cGMP-PKG signaling pathway
|
|
Neuroactive ligand-receptor interaction
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AMPK signaling pathway
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Adrenergic signaling in cardiomyocytes
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Vascular smooth muscle contraction
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Salivary secretionhsa04020:Calcium signaling pathway
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Salivary secretion
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NetPath Pathway
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IL2 Signaling PathwayNetPath_14:IL2 Signaling Pathway
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PANTHER Pathway
|
Alpha adrenergic receptor signaling pathwayP00002:Alpha adrenergic receptor signaling pathway
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Pathway Interaction Database
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LPA receptor mediated events
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|
Reactome
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Adrenoceptors
|
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G alpha (q) signalling events
|
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G alpha (12/13) signalling eventsR-HSA-390696:Adrenoceptors
|
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G alpha (12/13) signalling events
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WikiPathways
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Monoamine GPCRs
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Calcium Regulation in the Cardiac Cell
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GPCRs, Class A Rhodopsin-like
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Gastrin-CREB signalling pathway via PKC and MAPK
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Endothelin Pathways
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GPCR ligand binding
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GPCR downstream signaling
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AMPK SignalingWP58:Monoamine GPCRs
|
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GPCRs, OtherWP58:Monoamine GPCRs
|
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Vitamin D Receptor Pathway
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|
AMPK Signaling
|
| References |
| REF 1 | Analogs of UK 14,304: Structural features responsible for alpha2 adrenoceptor activity, Bioorg. Med. Chem. Lett. 5(15):1745-1750 (1995). |
|---|
