Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D02IMZ
|
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| Former ID |
DNC007462
|
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| Drug Name |
MCL-443
|
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| Drug Type |
Small molecular drug
|
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| Indication | Discovery agent | Investigative | [528655] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C29H36N2O2
|
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| Canonical SMILES |
C1CCC23CCN(C(C2C1)CC4=C3C=C(C=C4)OC(=O)NCC5=CC=CC=C5)CC<br />6CCC6
|
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| InChI |
1S/C29H36N2O2/c32-28(30-19-21-7-2-1-3-8-21)33-24-13-12-23-17-27-25-11-4-5-14-29(25,26(23)18-24)15-16-31(27)20-22-9-6-10-22/h1-3,7-8,12-13,18,22,25,27H,4-6,9-11,14-17,19-20H2,(H,30,32)
|
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| InChIKey |
VTNMTWBEHGIRGV-UHFFFAOYSA-N
|
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Mu-type opioid receptor | Target Info | Inhibitor | [528655] | |
| Kappa-type opioid receptor | Target Info | Inhibitor | [528655] | ||
| Delta-type opioid receptor | Target Info | Inhibitor | [528655] | ||
| NetPath Pathway | TCR Signaling Pathway | ||||
| PANTHER Pathway | Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | ||||
| Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway | |||||
| Enkephalin releaseP00026:Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | |||||
| Opioid prodynorphin pathwayP00026:Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | |||||
| Enkephalin release | |||||
| Opioid proenkephalin pathway | |||||
| Opioid proopiomelanocortin pathway | |||||
| Pathway Interaction Database | IL4-mediated signaling events | ||||
| References | |||||
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