Drug Information
Drug General Information | |||||
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Drug ID |
D02BBC
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Former ID |
DIB016149
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Drug Name |
CL-329167
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Synonyms |
2-Butyl-6-(1-methoxy-1-methylethyl)-3-[2'-(1H-tetrazol-5-yl)biphenyl-4-ylmethyl]quinazolin-4(3H)-one
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Drug Type |
Small molecular drug
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Indication | Hypertension [ICD9: 401; ICD10:I10-I16] | Phase 2 | [545836] | ||
Structure |
Download2D MOL |
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Formula |
C30H32N6O2
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Canonical SMILES |
CCCCC1=Nc2ccc(cc2C(=O)N1Cc3ccc(cc3)c4ccccc4c5nn[nH]n5)C<br />(C)(C)OC
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InChI |
1S/C30H32N6O2/c1-5-6-11-27-31-26-17-16-22(30(2,3)38-4)18-25(26)29(37)36(27)19-20-12-14-21(15-13-20)23-9-7-8-10-24(23)28-32-34-35-33-28/h7-10,12-18H,5-6,11,19H2,1-4H3,(H,32,33,34,35)
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InChIKey |
XZCUIMYYMKTCBA-UHFFFAOYSA-N
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CAS Number |
CAS 143945-39-5
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PubChem Compound ID | |||||
Target and Pathway | |||||
Target(s) | Type-1 angiotensin II receptor | Target Info | Antagonist | [533874], [551871] | |
NetPath Pathway | TGF_beta_Receptor Signaling Pathway | ||||
Pathway Interaction Database | Arf6 trafficking events | ||||
Arf6 signaling events | |||||
Angiopoietin receptor Tie2-mediated signaling | |||||
PathWhiz Pathway | Angiotensin Metabolism | ||||
Muscle/Heart Contraction | |||||
References |
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