Drug Information
Drug General Information | |||||
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Drug ID |
D01KPV
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Former ID |
DAP000330
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Drug Name |
Fexofenadine
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Synonyms |
Carboxyterfenadine; Fexofendine; Terfenadine acid metabolite; Terfenadine carboxylate; F 9427; MDL 16455; Allegra (TN); Fastofen (TN); Fexofenadine (INN); Fexofenadine [INN:BAN]; Telfast (TN); Terfenadine-COOH; Terfenidine carboxylate, MDL 16455; Tilfur (TN); 2-[4-(1-hydroxy-4-{4-[hydroxy(diphenyl)methyl]piperidin-1-yl}butyl)phenyl]-2-methylpropanoic acid; 2-[4-[1-hydroxy-4-[4-[hydroxy(diphenyl)methyl]piperidin-1-yl]butyl]phenyl]-2-methylpropanoic acid; 4-(1-Hydroxy-4-(4-(hydroxydiphenylmethyl)-1-piperidinyl)butyl)-alpha,alpha-dimethylbenzeneacetic acid
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Drug Type |
Small molecular drug
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Therapeutic Class |
Antiallergic Agents
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Company |
Sanofi-Aventis
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Structure |
Download2D MOL |
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Formula |
C32H39NO4
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InChI |
InChI=1S/C32H39NO4/c1-31(2,30(35)36)25-17-15-24(16-18-25)29(34)14-9-21-33-22-19-28(20-23-33)32(37,26-10-5-3-6-11-26)27-12-7-4-8-13-27/h3-8,10-13,15-18,28-29,34,37H,9,14,19-23H2,1-2H3,(H,35,36)
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InChIKey |
RWTNPBWLLIMQHL-UHFFFAOYSA-N
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CAS Number |
CAS 83799-24-0
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PubChem Compound ID | |||||
PubChem Substance ID |
9212, 5309243, 8152130, 11364860, 11367422, 11369984, 11372841, 11373946, 11378153, 11484933, 11488995, 11491736, 11492019, 11495728, 14835656, 17405051, 29222483, 46504676, 47953966, 48029199, 48029200, 49846688, 49878780, 50105687, 50105688, 53777594, 53787836, 57321745, 75782525, 85164717, 85209576, 85231056, 85789329, 90341422, 92304031, 93626300, 96024653, 103238871, 104303248, 117867878, 121361161, 124749753, 124880162, 124880163, 124891597, 125727652, 126525323, 126683996, 127278637, 127278638
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ChEBI ID |
ChEBI:5050
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SuperDrug ATC ID |
R06AX26
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SuperDrug CAS ID |
cas=083799240
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Target and Pathway | |||||
Target(s) | Histamine H1 receptor | Target Info | Antagonist | [535660], [537072] | |
PANTHER Pathway | Histamine H1 receptor mediated signaling pathway | ||||
References | |||||
Ref 468050 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4819). | ||||
Ref 534869 | Comparative tolerability of second generation antihistamines. Drug Saf. 1999 May;20(5):385-401. |
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