Drug Information
Drug General Information | |||||
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Drug ID |
D00UBK
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Former ID |
DNC005877
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Drug Name |
L-159689
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Drug Type |
Small molecular drug
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Indication | Hypertension [ICD9: 401; ICD10:I10-I16] | Terminated | [545497] | ||
Structure |
Download2D MOL |
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Formula |
C37H37N7O2
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Canonical SMILES |
CCCCCN(C1=CC2=C(C=C1)N=C(N(C2=O)CC3=CC=C(C=C3)C4=CC=CC=<br />C4C5=NNN=N5)CCC)C(=O)C6=CC=CC=C6
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InChI |
1S/C37H37N7O2/c1-3-5-11-23-43(36(45)28-13-7-6-8-14-28)29-21-22-33-32(24-29)37(46)44(34(38-33)12-4-2)25-26-17-19-27(20-18-26)30-15-9-10-16-31(30)35-39-41-42-40-35/h6-10,13-22,24H,3-5,11-12,23,25H2,1-2H3,(H,39,40,41,42)
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InChIKey |
JQXJNTQZCWEHKS-UHFFFAOYSA-N
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PubChem Compound ID | |||||
Target and Pathway | |||||
Target(s) | Type-1 angiotensin II receptor | Target Info | Inhibitor | [527799] | |
Type-2 angiotensin II receptor | Target Info | Inhibitor | [551315] | ||
NetPath Pathway | TGF_beta_Receptor Signaling Pathway | ||||
Pathway Interaction Database | Arf6 trafficking events | ||||
Arf6 signaling events | |||||
Angiopoietin receptor Tie2-mediated signaling | |||||
PathWhiz Pathway | Angiotensin Metabolism | ||||
Muscle/Heart Contraction | |||||
References |
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