Drug Information

Drug General Information
Drug ID
D00DNT
Former ID
DNC008374
Drug Name
JWH-406
Drug Type
Small molecular drug
Indication Discovery agent Investigative [529084]
Structure
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2D MOL

3D MOL
Formula
C20H32O
Canonical SMILES
CCCCCC(C)(C)C1=CC=C(C=C1)C2CCCC(C2)O
InChI
1S/C20H32O/c1-4-5-6-14-20(2,3)18-12-10-16(11-13-18)17-8-7-9-19(21)15-17/h10-13,17,19,21H,4-9,14-15H2,1-3H3/t17-,19-/m1/s1
InChIKey
RGRMJFXCHLLHAS-IEBWSBKVSA-N
PubChem Compound ID
44452581
Target and Pathway
Target(s) Cannabinoid receptor 2 Target Info Inhibitor [529084]
Cannabinoid receptor 1 Target Info Inhibitor [529084]
KEGG Pathway Neuroactive ligand-receptor interactionhsa04015:Rap1 signaling pathway
Neuroactive ligand-receptor interaction
Retrograde endocannabinoid signaling
PANTHER Pathway Endogenous cannabinoid signaling
Pathway Interaction Database N-cadherin signaling events
Reactome Class A/1 (Rhodopsin-like receptors)
G alpha (i) signalling eventsR-HSA-373076:Class A/1 (Rhodopsin-like receptors)
G alpha (i) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Small Ligand GPCRs
GPCR ligand binding
GPCR downstream signalingWP455:GPCRs, Class A Rhodopsin-like
BDNF signaling pathway
GPCR downstream signaling
GPCRs, Other
References
Ref 529084Bioorg Med Chem. 2008 Jan 1;16(1):322-35. Epub 2007 Sep 22.Synthesis and pharmacology of 1-deoxy analogs of CP-47,497 and CP-55,940.
Ref 529084Bioorg Med Chem. 2008 Jan 1;16(1):322-35. Epub 2007 Sep 22.Synthesis and pharmacology of 1-deoxy analogs of CP-47,497 and CP-55,940.

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